-
Deep neural networks for ECG interpretation and home cardiac monitoring
Development of deep neural networks for automated analysis of electrocardiograms (ECGs) and of a medical device to obtain a multi-lead device at home. Both innovations will be... -
De Hartenbank
De Hartenbank is een centrale biobank die hartweefsel van overleden donoren verzamelt en opslaat voor wetenschappelijk onderzoek. Met dit hartweefsel bekijken onderzoekers hoe... -
Technology Of Protein delivery through Extracellular Vesicles to target PCSK9
High total cholesterol levels are a major cause of disease burden in both the developed and developing world as a risk factor for ischemic heart disease and stroke. Lowering... -
Outflow tract related aging with congenital heart defects: identifying...
DCVA sample collection Outflow tract related aging with congenital heart defects: identifying causes and mechanisms of myocardial and large vessel wall adaptation, predictors... -
Atriumfibrilleren registratie
De Atriumfibrilleren registratie omvat patiënten met de novo atriumfibrilleren en/of atriumflutter. Het betreft patiënten (18 jaar of ouder) met een eerste AF / atriumflutter... -
Cardiochirurgie registratie
De Cardiochirurgie registratie omvat uitgevoerde cardiochirurgische ingrepen aan het hart en/of de grote intrathoracale vaten, al dan niet in combinatie met een niet-cardiale... -
ESCAPE-HF
large small molecule screen to identify compounds that enhance 5-oxoprolinase activity. -
Endocarditis registratie
De Endocarditis registratie omvat elke patiënt die binnen het endocarditis team wordt besproken, waarbij de diagnose ‘possible’ of ‘definite’ infectieuze endocarditis (IE) wordt... -
Inflammatory Reprogramming by Ageing and Microbiome - Targets for Treatment...
IN-CONTROL II will seek to i. unravel the mechanisms driving 'trained immunity" in patients, taking into account the impact of senescence, age, gender and obesity, ii. elucidate... -
EaRly diagnosis of Stable and Unstable Angina uSIng extracellular VEsicles
Extracellular vesicle proteins in plasma subfractions are investigated to determine their ability for early diagnosis of stable and unstable angina using a blood test -
DEFENCE: Determination and Evaluation of the Frequency and Effects of...
With our project we strive to maximally utilize existing data and registries. However, new data needs to be collected, primarily due to three reasons: (1) routine clinical care... -
Improved Prognosis of Vascular cognitive impairment using automatic...
To optimally use brain imaging data in vascular cognitive impairment (VCI), the ImProVas project (i) develops and validates methods for automatic quantification of microbleeds... -
Automatic CTA Image Analysis to Support Treatment Selection in Acute Stroke
Proper treatment selection in the acute phase of ischemic stroke can considerably improve patient outcome, as shown by recent studies. In the setting of acute stroke, treatment... -
CAPACITY-COVID
CAPACITY is a registry of patients with COVID-19 across Europe and has been established to answer questions on the role of cardiovascular disease in this pandemic. It is an... -
Lifestyle Innovations Based on youth's Knowledge and Experience
In the five year LIKE programme (2017-2022), we develop, implement and evaluate an integrated action programme at the level of family, school, neighbourhood, health care and... -
GENIUS II
We have from the atheroexpress biobank (UMCU) cell isolates from atherectomy samples and blood cells -
COroNary Calcium scoring as fiRst-linE Test to dEtect and exclude coronary...
CONCRETE aims to evaluate whether GP access to CT calcium scoring leads to earlier CAD diagnosis and treatment. The design is a pragmatic cluster randomized trial in which... -
UNRAVELLING AETIOLOGY AND RISK FACTORS IN PATIENTS WITH A BICUSPID AORTIC VALVES
The bicuspid aortic valve is generally considered to be a result of a congenital fusion of two out of three leaflets. We found that the non-coronary leaflet develops from the... -
Detection Of Latent Pulmonary Hypertension In Genetically Susceptible Individuals
longitudinal follow-up program for early detection of PAH in unaffected carriers. these carriers are compared with Idiopathic PAH patients, heritable PAH patients and healthy... -
IMPRESS
This project aims at investigating if the mechanism of trained immunity plays a role in the development of atherosclerosis in women with former preeclampsia.