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Inflammatory Reprogramming by Ageing and Microbiome - Targets for Treatment...
IN-CONTROL II will seek to i. unravel the mechanisms driving 'trained immunity" in patients, taking into account the impact of senescence, age, gender and obesity, ii. elucidate... -
EaRly diagnosis of Stable and Unstable Angina uSIng extracellular VEsicles
Extracellular vesicle proteins in plasma subfractions are investigated to determine their ability for early diagnosis of stable and unstable angina using a blood test -
DEFENCE: Determination and Evaluation of the Frequency and Effects of...
With our project we strive to maximally utilize existing data and registries. However, new data needs to be collected, primarily due to three reasons: (1) routine clinical care... -
CAPACITY-COVID
CAPACITY is a registry of patients with COVID-19 across Europe and has been established to answer questions on the role of cardiovascular disease in this pandemic. It is an... -
Detection Of Latent Pulmonary Hypertension In Genetically Susceptible Individuals
longitudinal follow-up program for early detection of PAH in unaffected carriers. these carriers are compared with Idiopathic PAH patients, heritable PAH patients and healthy... -
IMPRESS
This project aims at investigating if the mechanism of trained immunity plays a role in the development of atherosclerosis in women with former preeclampsia. -
PREDICT2
To improve treatment of ventricular arrhythmias, research is conducted on many different levels: genetics, basic and clinical electrophysiology, national registries, human samples. -
Outflow tract related aging with congenital heart defects: identifying...
Rationale: Whilst patients with a tetralogy of Fallot have excellent survival in the present day, adverse events still occur regularly. However,risk stratification in these... -
CVON ARGUS
CCTA and adenosine CMR imaging of women and men with chest pain symptoms -
ENERGISE, Targeting energy metabolism to combat cardiovascular disease
this is not one project but a collection of cohort studies, human experimental words and much more -
DETERMINANTS OF SUSCEPTIBILITY IN INHERITED CARDIOMYOPATHY: TOWARDS NOVEL...
Inherited cardiomyopathies (CM) are clinically heterogeneous: age of onset and disease-severity differ greatly between patients with the exact same gene mutation. The mechanisms... -
DETECTIN-HF
Dilated cardiomyopathy is a major cause of heart failure and is the main indication of cardiac transplantation. About 30-50% of the cases can be explained by genetic... -
Atrial Fibrillation Fingerprinting
Atrial fibrillation (AF) is the most common age-related cardiac rhythm disorder accounting for about one-third of rhythm abnormalities related hospitalizations with annual costs... -
Optimal Early Recognition of persons at high risk of Aneurysmal Subarachnoid...
ERASE will deliver: 1. Knowledge if we should also offer screening for intracranial aneurysms (IA) to persons 1. who have a positive family history with first degree relatives... -
REVIVING EARLY DIAGNOSIS OF CARDIOVASCULAR DISEASE
A diagnostic cluster randomized trial in patients participating in primary care disease management programs for COPD or type 2 diabetes. An early diagnosis strategy will be... -
Cardiac complications in Patients with SARS Corona virus 2 registry
The aim of CAPACITY is to collect data regarding the cardiovascular history, diagnostic information and occurrence of cardiovascular complications in COVID-19 patients. By... -
Determination and Evaluation of the Frequency and Effects of myocardial...
Within DEFENCE, all large national COVID-19 studies aimed at unravelling the relationship between cardiovascular disease and COVID-19 are brought together. The main aim of... -
Detection Of Latent Pulmonary Hypertension In Genetically Susceptible Individuals
longitudinal follow-up program for unaffected mutation carriers at risk for developing pulmonary arterial hypertension -
Dutch national consortium to promote cardiovascular healthy ageing in women
In CREW we addressed the following topics: - The prevalence of (subclinical) CVD in middle-aged women with PCOS/POI - The prevalence of (subclinical) CVD in middle-aged women... -
Heart-Brain Connection & Heart-Brain Connection - crossroads
Cognitive impairment is common among people with cardiovascular or cerebrovascular disease. HBC1 explored the etiological role of hemodynamic factors in cognitive impairment,...