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BRAIN@Risk
Functional and structural MRI biomarkers of large and small vessel disease of the cerebral vasculature. -
RADAR: Earlier Recognition of Aortic Dissection and Aneurysm Rupture: The RADAR Study
Aortic aneurysm is a life-threatening condition. When undetected, an aneurysm can grow and evolve into dissection or rupture. This RADAR-consortium will develop methods to... -
DETECTIN-HF
Dilated cardiomyopathy is a major cause of heart failure and is the main indication of cardiac transplantation. About 30-50% of the cases can be explained by genetic... -
Recognizing sudden cardiac arrest vulnerability in diabetes
The RESCUED study investigates the risk of a sudden cardiac arrest in diabetes patients. The aim is to improve recognition of individuals at high risk of sudden cardiac arrest... -
EaRly diagnosis of Stable and Unstable Angina uSIng extracellular VEsicles
Extracellular vesicle proteins in plasma subfractions are investigated to determine their ability for early diagnosis of stable and unstable angina using a blood test -
Inflammatory Reprogramming by Ageing and Microbiome - Targets for Treatment...
IN-CONTROL II will seek to i. unravel the mechanisms driving 'trained immunity" in patients, taking into account the impact of senescence, age, gender and obesity, ii. elucidate... -
UNRAVELLING AETIOLOGY AND RISK FACTORS IN PATIENTS WITH A BICUSPID AORTIC VALVES
The bicuspid aortic valve is generally considered to be a result of a congenital fusion of two out of three leaflets. We found that the non-coronary leaflet develops from the... -
Digoxin Evaluation in Chronic heart failure: Investigational Study In...
To invetigate if Low-dose Digoxin can effectively reduce cardiovascular mortality and recurrent HF hospitalizations, on top of the guideline-recommended therapies in HF patients... -
Circulating Nanotraces to Identify the Cause of Stroke
To develop a liquid biopsy biomarker that can differentiate between the cause of stroke (ischemic and hemorrhagic stroke) in the acute phase, new technology will be developed... -
Pulmonary Hypertension and AssociatED Right heart fAilure: IMproved outcomes...
PAH is a deadly disease characterized by abnormal remodelling of pulmonary vessels, leading to a progressive increase in pulmonary artery pressure and right heart failure.... -
Atrial Fibrillation Fingerprinting
Atrial fibrillation (AF) is the most common age-related cardiac rhythm disorder accounting for about one-third of rhythm abnormalities related hospitalizations with annual costs... -
DETERMINANTS OF SUSCEPTIBILITY IN INHERITED CARDIOMYOPATHY: TOWARDS NOVEL...
Inherited cardiomyopathies (CM) are clinically heterogeneous: age of onset and disease-severity differ greatly between patients with the exact same gene mutation. The mechanisms... -
ANEURYSM@RISK: automatic intracranial aneurysm quantification, 4D flow MRI...
We aim to improve rupture risk prediction by technical innovations 1) enabling automatic assessment of the UIA shape (including size), 2) determining the effect of the bloodflow... -
PREDICT2
To improve treatment of ventricular arrhythmias, research is conducted on many different levels: genetics, basic and clinical electrophysiology, national registries, human samples. -
Heart-Brain Connection & Heart-Brain Connection - crossroads
Cognitive impairment is common among people with cardiovascular or cerebrovascular disease. HBC1 explored the etiological role of hemodynamic factors in cognitive impairment,... -
QRS vectors in Solving the Inverse Problem of Electrocardiography
Electrocardiographic imaging in patients to identify early signs of disease in arrhytmogenic cardiomyopathy. Therefore, clinical MRI/CT, body surface mapping (64-electrode ECG)... -
BENEFIT for all: The Ecosystem for Healthy Living
BENEFIT is an ecosystem for healthy living and an integrated loyalty program that rewards patients for the time and energy spent on healthy lifestyle activities. By rewarding... -
Early detection of cardiac dysfunction in childhood cancer survivors; a LATER study
We collected cardiac data (history, phusica; examination, Echo, ECG, Blood) from 1550 chidlhood cancer survivors and 250 sibling.