617 datasets gevonden

Background The faecal immunochemical test (FIT) is widely employed for colorectal cancer screening. However, its sensitivity for advanced precursor lesions remains suboptimal....

Purpose: Circulating tumor DNA (ctDNA) has the potential to guide therapy selection and monitor treatment response in patients with metastatic cancer. However, germline and...

Hebon, initiated by NKI-AVL in 1997, is an active multidisciplinary collaboration of Clinical Genetics and laboratory departments of all University Medical Centers in the...

The Amsterdam Dementia Cohort was established in 2000, along with the foundation of the VU University Medical Center (VUmc) Alzheimer Center in the Netherlands. All patients...

Data collection of the ABOARD Cohort started in 2022 and is ongoing. Participants receive annual online questionnaires on (mental) health, quality of life, and use of healthcare...

"This study investigated the molecular landscape of 17 tumors from 9 individuals with biallelic germline pathogenic variants in CHEK2. Tumors included breast and non-breast...

300-Obese cohort was recruited at the Radboud University Medical Center (RUMC), Nijmegen, the Netherlands. The cohort comprises 377 participants included by the following...

Data van het Parkinson Op Maat cohort, inclusief klinische data, neuroimaging, biomaterialen en wearable data.

Data van het Nederlands RBD cohort, inclusief klinische data, neuroimaging, biomaterialen en wearable data.

Whole exome sequencing of 17 tumors from 12 different individuals with biallelic germline NTHL1 mutations from 9 different tissue types. Provided are 17 bam files which are...

Single saliva samples for cortisol analyses collected in 2012-2020 in subgroup (N~3400). Partially analyzed, remaining samples stored at -20°C.

The PRISMA imaging data consists of both processed and unprocessed screening mammograms (two views of each breast for each participant) obtained at study entry.

Whole exome sequencing data from the tumors (n=16) of individuals with constitutional mismatch repair deficiency. Data was aligned to GRCh38.

EDTA and heparin plasma samples were collected at 3 (n=1280) and 15 months (n=1122) after diagnosis. Heparin plasma samples have been analysed for carotenoids at 3 and 15 months...

Wearable data of the Personalized Parkinson Project, including data obtained with a Verily watch.

Subproject among 116 PRIDE Study participants. Gut microbiome data for maternal samples collected at gestational weeks 20 and 34, and 2 months after the estimated date of...

Isolated DNA and genome-wide germline SNP data is available for 1213 patients.

Patients with localized stage I-III renal cell cancer (n=365) completed paper-and-pencil or web-based questionnaires at 3 months (n=368), 12 months (n=317), and 24 months...

6-week medication diaries covering prescription and over-the counter use, administered in the second trimester of pregnancy. Available for 1516 PRIDE Study participants...

Molecular subtype based on immunohistrochemistry performed on tissue microarrays is available for 389 T1 NMIBC tumours.