Continuous monitoring of short-term variability of repolarization for prediction and prevention of ventricular arrhythmias and sudden cardiac death.

We propose a new treatment methodology that 1) is able to predict an upcoming ventricular tachy-arrhythmic event and 2) can initiate a preventive intervention. This methodology can be built into an ICD and uses beat-to-beat variability of repolarization quantified as short-term variability (STV) to continuously monitor the repolarization reserve of the heart. When a ventricular arrhythmia is forthcoming, this algorithm can activate the ICD to temporarily pace the heart at a higher frequency, thereby restoring/improving the repolarization strength of the heart and preventing the arrhythmia from occurring.

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Veld	Waarde
Titel	Continuous monitoring of short-term variability of repolarization for prediction and prevention of ventricular arrhythmias and sudden cardiac death.
Omschrijving	We propose a new treatment methodology that 1) is able to predict an upcoming ventricular tachy-arrhythmic event and 2) can initiate a preventive intervention. This methodology can be built into an ICD and uses beat-to-beat variability of repolarization quantified as short-term variability (STV) to continuously monitor the repolarization reserve of the heart. When a ventricular arrhythmia is forthcoming, this algorithm can activate the ICD to temporarily pace the heart at a higher frequency, thereby restoring/improving the repolarization strength of the heart and preventing the arrhythmia from occurring.
Keywords	Female Male Not available Other Physiological... STV 24 7 Sudden cardiac death so described
Contact points	Contact point 1 URI Naam DCVA Name (translations) Email info@dcvalliance.nl Identifier URL https://www.dcvalliance.nl/
Publisher	Publisher 1 URI Naam Dutch Cardiovascular Alliance (DCVA) Name (translations) Email info@dcvalliance.nl URL https://www.dcvalliance.nl/ Type Publisher note Publisher type Identifier DCVA
Creator	Creator 1 URI Naam Dutch Cardiovascular Alliance (DCVA) Name (translations) Email info@dcvalliance.nl URL https://www.dcvalliance.nl/ Type Publisher note Publisher type Identifier DCVA
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Release date	2018-11-01T00:00:00+00:00
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Identifier	DCVA-038
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Type
Temporal coverage	Temporal coverage 1 Start 2018-11-01T00:00:00+00:00 End 2021-11-01T00:00:00+00:00
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Spatial coverage	Spatial coverage 1 URI http://publications.europa.eu/resource/authority/country/NLD Label Geometry Bounding Box Centroid
Spatial resolution in meters
Access rights	http://publications.europa.eu/resource/authority/access-right/RESTRICTED
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Theme	http://publications.europa.eu/resource/authority/data-theme/HEAL
Taal	http://id.loc.gov/vocabulary/iso639-1/en
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Applicable legislation	http://data.europa.eu/eli/reg/2025/327/oj
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Minimum typical age	1
Maximum typical age	2
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Population coverage	collection type: Other \| disease: Sudden cardiac death, so described \| data categories: Physiological/Biochemical measurements \| materials: Not available \| omics: Not available \| imaging: N \| sex: Female,Male
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Qualified attribution	Attribution 1 Agent Agent 1 URI Naam Dutch Cardiovascular Alliance (DCVA) Name (translations) Email info@dcvalliance.nl URL https://www.dcvalliance.nl/ Homepage Type Identifier DCVA Rol
Quality annotations
URI	https://fdp.heart-institute.nl/dataset/d76cc8d7-7950-47a5-b612-6b359b76a695