Celiac disease meta-analysis

Celiac disease (CeD) is a common immune-mediated disease of the small intestine that is triggered by exposure to dietary gluten. While the HLA locus plays a major role in disease susceptibility, 39 non-HLA loci were also identified in a study of 24,269 individuals. We now build on this earlier study by adding 4,125 additional Caucasian samples including an Argentinian cohort genotyped on the Immunochip. In doing so, we not only confirm the previous associations, we also identify two novel independent genome-wide significant associations.

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Title Celiac disease meta-analysis
Description

Celiac disease (CeD) is a common immune-mediated disease of the small intestine that is triggered by exposure to dietary gluten. While the HLA locus plays a major role in disease susceptibility, 39 non-HLA loci were also identified in a study of 24,269 individuals. We now build on this earlier study by adding 4,125 additional Caucasian samples including an Argentinian cohort genotyped on the Immunochip. In doing so, we not only confirm the previous associations, we also identify two novel independent genome-wide significant associations.
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Contact point 1
URI
http://umcgresearchdatacatalogue.nl/catalogue_rdf/api/rdf/Contacts/firstName=Iris&lastName=Jonker&resource=EGAS00001003805
Name
Iris Jonker
Name (translations)
Email
i.h.jonkers@umcg.nl
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URL
Publisher
Publisher 1
URI
http://umcgresearchdatacatalogue.nl/catalogue_rdf/api/rdf/Agents/id=UMCG&resource=EGAS00001003805
Name
University Medical Center Groningen
Name (translations)
Email
researchdatacatalogue@umcg.nl
URL
https://www.umcg.nl/
Type
Identifier
https://ror.org/03cv38k47
Creator
Creator 1
URI
http://umcgresearchdatacatalogue.nl/catalogue_rdf/api/rdf/Agents/id=UMCG&resource=EGAS00001003805
Name
University Medical Center Groningen
Name (translations)
Email
researchdatacatalogue@umcg.nl
URL
https://www.umcg.nl/
Type
Identifier
https://ror.org/03cv38k47
Landing page https://ega-archive.org/studies/EGAS00001003805
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    Identifier https://metadata.ega-archive.org/studies/EGAS00001003805
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    Spatial resolution in meters
    Access rights http://publications.europa.eu/resource/authority/access-right/NON_PUBLIC
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    1. http://publications.europa.eu/resource/authority/data-theme/HEAL
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    1. http://data.europa.eu/eli/reg/2022/868/oj
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    Health category
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    URI http://umcgresearchdatacatalogue.nl/catalogue_rdf/api/rdf/Resources/id=EGAS00001003805