@prefix adms: <http://www.w3.org/ns/adms#> .
@prefix dcat: <http://www.w3.org/ns/dcat#> .
@prefix dcatap: <http://data.europa.eu/r5r/> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .
@prefix healthdcatap: <http://healthdataportal.eu/ns/health#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix vcard: <http://www.w3.org/2006/vcard/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://fdp.heart-institute.nl/dataset/122cc950-ae28-452e-93e8-ee51bbaaac5d> a dcat:Dataset ;
    dcatap:applicableLegislation <http://data.europa.eu/eli/reg/2025/327/oj> ;
    healthdcatap:maxTypicalAge "90"^^xsd:nonNegativeInteger ;
    healthdcatap:minTypicalAge "18"^^xsd:nonNegativeInteger ;
    healthdcatap:numberOfUniqueIndividuals "1802"^^xsd:nonNegativeInteger ;
    healthdcatap:populationCoverage "collection type: Birth cohort,Cohort,Disease specific,Non-Human,Population-based | disease: Atherosclerosis,Obesity | data categories: Biological samples,Imaging data,Physiological/Biochemical measurements | materials: cDNA / mRNA,DNA,Feaces,Peripheral blood cells,Plasma,RNA,Serum,Tissue, cryo preserved,Tissue, paraffin preserved | omics: Genomics,Metabolomics,Proteomics,Transcriptomics | imaging: Y | sex: Female,Male"@en ;
    dct:accessRights <http://publications.europa.eu/resource/authority/access-right/RESTRICTED> ;
    dct:creator [ a foaf:Agent ;
            dct:identifier "DCVA" ;
            vcard:hasEmail <mailto:info@dcvalliance.nl> ;
            foaf:homepage <https://www.dcvalliance.nl/> ;
            foaf:name "Dutch Cardiovascular Alliance (DCVA)" ] ;
    dct:description "IN-CONTROL II will seek to i. unravel the mechanisms driving 'trained immunity\" in patients, taking into account the impact of senescence, age, gender and obesity, ii. elucidate the interactions between microbiome-derived signals and (immune) senescence in the etiology of obesity-related cardio-metabolic diseases, and iii. to pursue and to identify new therapeutic targets and to design novel pharmacological and microbiome-based therapies to counteract inappropriate induction of trained immunity and inflammatory processes in cardiovascular disease."@en,
        ""@nl ;
    dct:identifier "DCVA-005" ;
    dct:issued "2019-05-01T00:00:00+00:00"^^xsd:dateTime ;
    dct:language <http://id.loc.gov/vocabulary/iso639-1/en> ;
    dct:modified "2026-04-13T14:01:55.881098"^^xsd:dateTime ;
    dct:provenance [ a dct:ProvenanceStatement ;
            rdfs:label ""@en,
                ""@nl ] ;
    dct:publisher [ a foaf:Agent ;
            dct:identifier "DCVA" ;
            vcard:hasEmail <mailto:info@dcvalliance.nl> ;
            foaf:homepage <https://www.dcvalliance.nl/> ;
            foaf:name "Dutch Cardiovascular Alliance (DCVA)" ] ;
    dct:spatial <http://publications.europa.eu/resource/authority/country/NLD> ;
    dct:temporal [ a dct:PeriodOfTime ;
            dcat:endDate "2024-04-30T00:00:00+00:00"^^xsd:dateTime ;
            dcat:startDate "2019-05-01T00:00:00+00:00"^^xsd:dateTime ],
        [ a dct:PeriodOfTime ;
            dcat:endDate "2024-04-30T00:00:00+00:00"^^xsd:dateTime ;
            dcat:startDate "2019-05-01T00:00:00+00:00"^^xsd:dateTime ] ;
    dct:title "Inflammatory Reprogramming by Ageing and Microbiome - Targets for Treatment of Cardiovascular Disease"@en,
        ""@nl ;
    adms:versionNotes ""@en,
        ""@nl ;
    dcat:contactPoint [ a vcard:Kind ;
            vcard:fn "DCVA" ;
            vcard:hasEmail <mailto:info@dcvalliance.nl> ;
            vcard:hasURL <https://www.dcvalliance.nl/> ] ;
    dcat:keyword "Atherosclerosis"@en,
        "Biological samples"@en,
        "Birth cohort"@en,
        "Cohort"@en,
        "DNA"@en,
        "Disease specific"@en,
        "Feaces"@en,
        "Female"@en,
        "Genomics"@en,
        "IN-CONTROL II"@en,
        "Imaging data"@en,
        "Male"@en,
        "Metabolomics"@en,
        "Non-Human"@en,
        "Obesity"@en,
        "Peripheral blood cells"@en,
        "Physiological Biochemical measurements"@en,
        "Plasma"@en,
        "Population-based"@en,
        "Proteomics"@en,
        "RNA"@en,
        "Serum"@en,
        "Tissue"@en,
        "Transcriptomics"@en,
        "cDNA   mRNA"@en,
        "cryo preserved"@en,
        "paraffin preserved"@en ;
    dcat:qualifiedAttribution [ a dcat:Attribution ;
            dcat:agent [ a foaf:Agent,
                        foaf:Organization ;
                    dct:identifier "DCVA" ;
                    foaf:homepage <https://www.dcvalliance.nl/> ;
                    foaf:mbox <mailto:info@dcvalliance.nl> ;
                    foaf:name "Dutch Cardiovascular Alliance (DCVA)" ] ] ;
    dcat:theme <http://publications.europa.eu/resource/authority/data-theme/HEAL> .

<http://data.europa.eu/eli/reg/2025/327/oj> a <http://data.europa.eu/eli/ontology#LegalResource> .

<http://id.loc.gov/vocabulary/iso639-1/en> a dct:LinguisticSystem .

<http://publications.europa.eu/resource/authority/access-right/RESTRICTED> a dct:RightsStatement .

<http://publications.europa.eu/resource/authority/country/NLD> a dct:Location .