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Deep neural networks for ECG interpretation and home cardiac monitoring
Development of deep neural networks for automated analysis of electrocardiograms (ECGs) and of a medical device to obtain a multi-lead device at home. Both innovations will be... -
EaRly diagnosis of Stable and Unstable Angina uSIng extracellular VEsicles
Extracellular vesicle proteins in plasma subfractions are investigated to determine their ability for early diagnosis of stable and unstable angina using a blood test -
DEFENCE: Determination and Evaluation of the Frequency and Effects of...
With our project we strive to maximally utilize existing data and registries. However, new data needs to be collected, primarily due to three reasons: (1) routine clinical care... -
CAPACITY-COVID
CAPACITY is a registry of patients with COVID-19 across Europe and has been established to answer questions on the role of cardiovascular disease in this pandemic. It is an... -
Lifestyle Innovations Based on youth's Knowledge and Experience
In the five year LIKE programme (2017-2022), we develop, implement and evaluate an integrated action programme at the level of family, school, neighbourhood, health care and... -
COroNary Calcium scoring as fiRst-linE Test to dEtect and exclude coronary...
CONCRETE aims to evaluate whether GP access to CT calcium scoring leads to earlier CAD diagnosis and treatment. The design is a pragmatic cluster randomized trial in which... -
UNRAVELLING AETIOLOGY AND RISK FACTORS IN PATIENTS WITH A BICUSPID AORTIC VALVES
The bicuspid aortic valve is generally considered to be a result of a congenital fusion of two out of three leaflets. We found that the non-coronary leaflet develops from the... -
Detection Of Latent Pulmonary Hypertension In Genetically Susceptible Individuals
longitudinal follow-up program for early detection of PAH in unaffected carriers. these carriers are compared with Idiopathic PAH patients, heritable PAH patients and healthy... -
IMPRESS
This project aims at investigating if the mechanism of trained immunity plays a role in the development of atherosclerosis in women with former preeclampsia. -
Video monitoring FOR early Signaling of adverse EvEnts
This project explores continuous video monitoring of the cardiorespiratory status of a patient as an innovative unobtrusive method that could aid to reduce workload for the... -
RADAR: Earlier Recognition of Aortic Dissection and Aneurysm Rupture: The RADAR Study
Aortic aneurysm is a life-threatening condition. When undetected, an aneurysm can grow and evolve into dissection or rupture. This RADAR-consortium will develop methods to... -
ECG-AI
Developing AI for ECG interpretation -
PREDICT2
To improve treatment of ventricular arrhythmias, research is conducted on many different levels: genetics, basic and clinical electrophysiology, national registries, human samples. -
Outflow tract related aging with congenital heart defects: identifying...
Rationale: Whilst patients with a tetralogy of Fallot have excellent survival in the present day, adverse events still occur regularly. However,risk stratification in these... -
Coronary ARtery disease: Risk estimations and Interventions for prevention...
CARRIER proposes a big data-driven approach to detection and prevention of coronary artery disease. Models learnt from big data will help identify patients at increased risk and... -
GeranylGeranylAcetone in Heart failure with preserved ejection fraction
In this phase 2 trial, we expect to obtain proof of concept for a beneficial effect of GGA on HFpEF. In HFpEF patients we will evaluate effects of GGA on signs and symptoms of... -
Perfect Fit: Targeting key risk factors for cardiovascular disease in...
Smoking and insufficient physical activity are key risk factors for cardiovascular disease. Perfect Fit uses big data science techniques to develop highly personalized and... -
Outflow tract related aging with congenital heart disease. Workpackage...
Rationale: Tetralogy of Fallot is the most common type of cyanotic congenital heart disease. The main problems of this patient population are heart failure related to chronic... -
Device-based rate versus rhythm control treatment in patients with...
multicenter, prospective randomised controlled trial to evaluate the efficacy of a watchful waiting strategy (rate control for symptom relief) compared to routine care... -
DOMESTICO prospectief
DOMESTICO or the Dutch nOcturnal and hoME dialysis Study To Improve Clinical Outcomes is a nationwide, combined retrospective and prospective, observational cohort study that...
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