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Outflow tract related aging with congenital heart defects: identifying...
Retrospective cohort study in patients with atrial switch operation, longitudinal Follow Up -
ANEURYSM@RISK: automatic intracranial aneurysm quantification, 4D flow MRI...
We aim to improve rupture risk prediction by technical innovations 1) enabling automatic assessment of the UIA shape (including size), 2) determining the effect of the bloodflow... -
GeranylGeranylAcetone in Heart failure with preserved ejection fraction
In this phase 2 trial, we expect to obtain proof of concept for a beneficial effect of GGA on HFpEF. In HFpEF patients we will evaluate effects of GGA on signs and symptoms of... -
PREDICT2
To improve treatment of ventricular arrhythmias, research is conducted on many different levels: genetics, basic and clinical electrophysiology, national registries, human samples. -
Recognizing sudden cardiac arrest vulnerability in diabetes
The RESCUED study investigates the risk of a sudden cardiac arrest in diabetes patients. The aim is to improve recognition of individuals at high risk of sudden cardiac arrest... -
Heart-Brain Connection & Heart-Brain Connection - crossroads
Cognitive impairment is common among people with cardiovascular or cerebrovascular disease. HBC1 explored the etiological role of hemodynamic factors in cognitive impairment,... -
Outflow tract related aging with congenital heart defects: identifying...
The CAS study is a clinical observational study investigating the effects of ConAoS on the left ventricular function and the prevalence, pattern and expanse of LVH, myocardial... -
CAPACITY-COVID
CAPACITY is a registry of patients with COVID-19 across Europe and has been established to answer questions on the role of cardiovascular disease in this pandemic. It is an... -
Colchicin in patients with chronic coronary disease
Double blind randomised clinical trial with colchicin/ placebo in patients with chronic coronary disease. 5552 Pts in Netherlands and Australia -
Early detection of cardiac dysfunction in childhood cancer survivors; a LATER study
We collected cardiac data (history, phusica; examination, Echo, ECG, Blood) from 1550 chidlhood cancer survivors and 250 sibling. -
Atrial Fibrillation Fingerprinting
Atrial fibrillation (AF) is the most common age-related cardiac rhythm disorder accounting for about one-third of rhythm abnormalities related hospitalizations with annual costs... -
BRAIN@Risk
Functional and structural MRI biomarkers of large and small vessel disease of the cerebral vasculature. -
Outflow tract related aging with congenital heart disease. Workpackage...
Rationale: Tetralogy of Fallot is the most common type of cyanotic congenital heart disease. The main problems of this patient population are heart failure related to chronic... -
IMPRESS
This project aims at investigating if the mechanism of trained immunity plays a role in the development of atherosclerosis in women with former preeclampsia. -
QRS vectors in Solving the Inverse Problem of Electrocardiography
Electrocardiographic imaging in patients to identify early signs of disease in arrhytmogenic cardiomyopathy. Therefore, clinical MRI/CT, body surface mapping (64-electrode ECG)... -
CAPACITY 2: A prospective cohort study evaluating the occurrence of short...
For this reason, there is an urgent need for large prospective cohort studies in which patients with laboratory confirmed COVID-19 unselectively undergo standardized and long-... -
Digoxin Evaluation in Chronic heart failure: Investigational Study In...
Investigation whether low-level, aiming for serum concentrations 0.5-0.9ng/mL, digoxin on top of standard treatment (guideline-recommended therapy), is beneficial in HF patients... -
DEFENCE: Determination and Evaluation of the Frequency and Effects of...
With our project we strive to maximally utilize existing data and registries. However, new data needs to be collected, primarily due to three reasons: (1) routine clinical care... -
UNRAVELLING AETIOLOGY AND RISK FACTORS IN PATIENTS WITH A BICUSPID AORTIC VALVES
The bicuspid aortic valve is generally considered to be a result of a congenital fusion of two out of three leaflets. We found that the non-coronary leaflet develops from the...
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