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DETECTIN-HF
Dilated cardiomyopathy is a major cause of heart failure and is the main indication of cardiac transplantation. About 30-50% of the cases can be explained by genetic... -
Recognizing sudden cardiac arrest vulnerability in diabetes
The RESCUED study investigates the risk of a sudden cardiac arrest in diabetes patients. The aim is to improve recognition of individuals at high risk of sudden cardiac arrest... -
Inflammatory Reprogramming by Ageing and Microbiome - Targets for Treatment...
IN-CONTROL II will seek to i. unravel the mechanisms driving 'trained immunity" in patients, taking into account the impact of senescence, age, gender and obesity, ii. elucidate... -
UNRAVELLING AETIOLOGY AND RISK FACTORS IN PATIENTS WITH A BICUSPID AORTIC VALVES
The bicuspid aortic valve is generally considered to be a result of a congenital fusion of two out of three leaflets. We found that the non-coronary leaflet develops from the... -
Race V - Poaf
primary aim: study molecular mechanisms of AF by combining histology, biochemical analysis, and genome-wide RNA expression profiles. Secondary aim: study the incidence of AF... -
Optimal Early Recognition of persons at high risk of Aneurysmal Subarachnoid...
ERASE will deliver: 1. Knowledge if we should also offer screening for intracranial aneurysms (IA) to persons 1. who have a positive family history with first degree relatives... -
GENIUS II
We have from the atheroexpress biobank (UMCU) cell isolates from atherectomy samples and blood cells -
Early detection of disease in cardiomyopathy mutation carriers
A campaign to inform the general public and online tools to evaluate indications for cardiogenetic referral will be launched. The yield of novel methods to reach out to family... -
DETERMINANTS OF SUSCEPTIBILITY IN INHERITED CARDIOMYOPATHY: TOWARDS NOVEL...
Inherited cardiomyopathies (CM) are clinically heterogeneous: age of onset and disease-severity differ greatly between patients with the exact same gene mutation. The mechanisms...
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