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CVON ARGUS
CCTA and adenosine CMR imaging of women and men with chest pain symptoms -
DETECTIN-HF
Dilated cardiomyopathy is a major cause of heart failure and is the main indication of cardiac transplantation. About 30-50% of the cases can be explained by genetic... -
EaRly diagnosis of Stable and Unstable Angina uSIng extracellular VEsicles
Extracellular vesicle proteins in plasma subfractions are investigated to determine their ability for early diagnosis of stable and unstable angina using a blood test -
Inflammatory Reprogramming by Ageing and Microbiome - Targets for Treatment...
IN-CONTROL II will seek to i. unravel the mechanisms driving 'trained immunity" in patients, taking into account the impact of senescence, age, gender and obesity, ii. elucidate... -
UNRAVELLING AETIOLOGY AND RISK FACTORS IN PATIENTS WITH A BICUSPID AORTIC VALVES
The bicuspid aortic valve is generally considered to be a result of a congenital fusion of two out of three leaflets. We found that the non-coronary leaflet develops from the... -
Race V - Poaf
primary aim: study molecular mechanisms of AF by combining histology, biochemical analysis, and genome-wide RNA expression profiles. Secondary aim: study the incidence of AF... -
Circulating Nanotraces to Identify the Cause of Stroke
To develop a liquid biopsy biomarker that can differentiate between the cause of stroke (ischemic and hemorrhagic stroke) in the acute phase, new technology will be developed... -
Pulmonary Hypertension and AssociatED Right heart fAilure: IMproved outcomes...
PAH is a deadly disease characterized by abnormal remodelling of pulmonary vessels, leading to a progressive increase in pulmonary artery pressure and right heart failure.... -
ENERGISE, Targeting energy metabolism to combat cardiovascular disease
this is not one project but a collection of cohort studies, human experimental words and much more -
Detection Of Latent Pulmonary Hypertension In Genetically Susceptible Individuals
longitudinal follow-up program for unaffected mutation carriers at risk for developing pulmonary arterial hypertension -
Atrial Fibrillation Fingerprinting
Atrial fibrillation (AF) is the most common age-related cardiac rhythm disorder accounting for about one-third of rhythm abnormalities related hospitalizations with annual costs... -
GENIUS II
We have from the atheroexpress biobank (UMCU) cell isolates from atherectomy samples and blood cells -
Early detection of disease in cardiomyopathy mutation carriers
A campaign to inform the general public and online tools to evaluate indications for cardiogenetic referral will be launched. The yield of novel methods to reach out to family... -
DETERMINANTS OF SUSCEPTIBILITY IN INHERITED CARDIOMYOPATHY: TOWARDS NOVEL...
Inherited cardiomyopathies (CM) are clinically heterogeneous: age of onset and disease-severity differ greatly between patients with the exact same gene mutation. The mechanisms... -
WOMB project: Women Offspring and iMproving lifestyle for Better...
Follow up of women (with obesity and unfulfilled wish for a child) and their children who participated in a preconception lifestyle intervention with focus on women's lifestyle,... -
Technology Of Protein delivery through Extracellular Vesicles to target PCSK9
High total cholesterol levels are a major cause of disease burden in both the developed and developing world as a risk factor for ischemic heart disease and stroke. Lowering... -
PREDICT2
To improve treatment of ventricular arrhythmias, research is conducted on many different levels: genetics, basic and clinical electrophysiology, national registries, human samples. -
Heart-Brain Connection & Heart-Brain Connection - crossroads
Cognitive impairment is common among people with cardiovascular or cerebrovascular disease. HBC1 explored the etiological role of hemodynamic factors in cognitive impairment,... -
REVIVING EARLY DIAGNOSIS OF CARDIOVASCULAR DISEASE
A diagnostic cluster randomized trial in patients participating in primary care disease management programs for COPD or type 2 diabetes. An early diagnosis strategy will be...
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