@prefix adms: <http://www.w3.org/ns/adms#> .
@prefix dcat: <http://www.w3.org/ns/dcat#> .
@prefix dcatap: <http://data.europa.eu/r5r/> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .
@prefix healthdcatap: <http://healthdataportal.eu/ns/health#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix vcard: <http://www.w3.org/2006/vcard/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<http://catalogue.hdsu.nl/catalogue-rdf/api/rdf/Resources/id=PRESENT%2B> a dcat:Dataset ;
    dcatap:applicableLegislation <http://data.europa.eu/eli/reg/2022/868/oj> ;
    healthdcatap:numberOfUniqueIndividuals "2700"^^xsd:nonNegativeInteger ;
    dct:accessRights <http://publications.europa.eu/resource/authority/access-right/NON_PUBLIC> ;
    dct:accrualPeriodicity <http://publications.europa.eu/resource/authority/frequency/CONT> ;
    dct:creator <http://catalogue.hdsu.nl/catalogue-rdf/api/rdf/Agents/id=EMC&resource=PRESENT%2B>,
        <http://catalogue.hdsu.nl/catalogue-rdf/api/rdf/Agents/id=LUMC&resource=PRESENT%2B>,
        <http://catalogue.hdsu.nl/catalogue-rdf/api/rdf/Agents/id=Radboudumc&resource=PRESENT%2B>,
        <http://catalogue.hdsu.nl/catalogue-rdf/api/rdf/Agents/id=UMCU&resource=PRESENT%2B> ;
    dct:description ""@en,
        "The PRESENT+ cohort is  a Dutch prospective multicenter cohort including patients with bone metastases referred to the departments of radiation oncology or orthopedic surgery. The cohort started in 2013 and is still ongoing. PRESENT+ follows the Trials within Cohorts (TwiCs) design and serves as an infrastructure for efficient and pragmatic (randomized) treatment evaluation. Clinical (follow-up) data and patient reported outcomes are collected prospectively."@nl ;
    dct:identifier <https://doi.org/10.71739/zhhy-9y29> ;
    dct:issued "2026-07-05T18:29:51.144861"^^xsd:dateTime ;
    dct:modified "2026-08-08T02:15:17.021170"^^xsd:dateTime ;
    dct:provenance [ a dct:ProvenanceStatement ;
            rdfs:label ""@en,
                """Trials within Cohorts (TwiCs)
At cohort inclusion, patients are asked informed consent for 1) use of routinely collected data including baseline demographics, disease and treatment characteristics, and clinical follow-up data, 2) prospective collection of patient-reported outcomes, and 3) randomization into future intervention studies where they will be offered the intervention when allocated to the intervention group, or serve as a control without notification."""@nl ] ;
    dct:publisher <http://catalogue.hdsu.nl/catalogue-rdf/api/rdf/Agents/id=UMCU&resource=PRESENT%2B> ;
    dct:spatial <http://catalogue.hdsu.nl/CatalogueOntologies/api/rdf/Regions/name=Utrecht> ;
    dct:title ""@en,
        "PRospective Evaluation of interventional StudiEs on boNe meTastases (PRESENT+)"@nl ;
    adms:versionNotes ""@en,
        ""@nl ;
    dcat:contactPoint <http://catalogue.hdsu.nl/catalogue-rdf/api/rdf/Contacts/firstName=Roxanne&lastName=Gal&resource=PRESENT%2B> ;
    dcat:keyword "QoL"@nl,
        "Trials within Cohorts"@nl,
        "TwiCs"@nl,
        "bone metastases"@nl,
        "cohort"@nl,
        "follow-up"@nl,
        "pain"@nl,
        "patient-reported outcomes"@nl,
        "proms"@nl,
        "prospective"@nl,
        "quality of life"@nl,
        "radiotherapy"@nl ;
    dcat:landingPage <https://clinicaltrials.gov/study/NCT02356497?cond=bone%20metastases&term=present&rank=1> ;
    dcat:theme <http://publications.europa.eu/resource/authority/data-theme/HEAL> .

<http://catalogue.hdsu.nl/CatalogueOntologies/api/rdf/Regions/name=Utrecht> a dct:Location .

<http://catalogue.hdsu.nl/catalogue-rdf/api/rdf/Agents/id=EMC&resource=PRESENT%2B> a foaf:Agent ;
    dct:identifier "ROR:018906e22" ;
    vcard:hasEmail <mailto:catalogue@hdsu.nl> ;
    foaf:homepage <https://www.erasmusmc.nl> ;
    foaf:name "Erasmus MC" .

<http://catalogue.hdsu.nl/catalogue-rdf/api/rdf/Agents/id=LUMC&resource=PRESENT%2B> a foaf:Agent ;
    dct:identifier "ROR:05xvt9f17" ;
    vcard:hasEmail <mailto:catalogue@hdsu.nl> ;
    foaf:homepage <https://www.lumc.nl> ;
    foaf:name "Leiden University Medical Center" .

<http://catalogue.hdsu.nl/catalogue-rdf/api/rdf/Agents/id=Radboudumc&resource=PRESENT%2B> a foaf:Agent ;
    dct:identifier "ROR:05wg1m734" ;
    vcard:hasEmail <mailto:catalogue@hdsu.nl> ;
    foaf:homepage <https://www.radboudumc.nl> ;
    foaf:name "Radboud University Medical Center" .

<http://catalogue.hdsu.nl/catalogue-rdf/api/rdf/Contacts/firstName=Roxanne&lastName=Gal&resource=PRESENT%2B> a vcard:Kind ;
    vcard:fn "Roxanne Gal" ;
    vcard:hasEmail <mailto:R.Gal@umcutrecht.nl> .

<http://data.europa.eu/eli/reg/2022/868/oj> a <http://data.europa.eu/eli/ontology#LegalResource> .

<http://publications.europa.eu/resource/authority/access-right/NON_PUBLIC> a dct:RightsStatement .

<http://publications.europa.eu/resource/authority/frequency/CONT> a dct:Frequency .

<https://clinicaltrials.gov/study/NCT02356497?cond=bone%20metastases&term=present&rank=1> a foaf:Document .

<http://catalogue.hdsu.nl/catalogue-rdf/api/rdf/Agents/id=UMCU&resource=PRESENT%2B> a foaf:Agent ;
    dct:identifier "ROR:0575yy874" ;
    vcard:hasEmail <mailto:info@umcutrecht.nl> ;
    foaf:homepage <https://www.umcutrecht.nl> ;
    foaf:name "University Medical Center Utrecht" .