CKAN
type: Catalog
language: en
modified: 2026-01-07T19:34:58.399870

FU survey Darmgezondheid (GSRS)
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:28:57+00:00
modified: 2024-11-12T14:29:46+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Marian Beekman
creator: Diana van Heemst
creator: Joris Deelen
creator: Eline Slagboom
creator: Simon Mooijaart

LLS_IOP3_OLINKcardiomatebolic_metadata
type: Dataset
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-02-09T08:28:35+00:00
modified: 2024-02-09T08:29:02+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Joris Deelen
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Marian Beekman
creator: Eline Slagboom

FU survey Gevoel en gedrag (CES-D)
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:19:43+00:00
modified: 2024-11-12T14:20:15+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Diana van Heemst
creator: Marian Beekman
creator: Joris Deelen
creator: Simon Mooijaart
creator: Eline Slagboom

FU_Castor_Thuis_vragenlijsten
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T13:24:18+00:00
modified: 2024-11-12T13:26:07+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Eline Slagboom
creator: Joris Deelen
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Marian Beekman

Global Metabolomics
type: Dataset
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:07:22+00:00
modified: 2024-11-07T14:09:32+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Marian Beekman
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Joris Deelen
creator: Diana van Heemst

SignalingLipids Overview
type: Dataset
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:12:43+00:00
modified: 2024-11-07T14:13:14+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Eline Slagboom
creator: Marian Beekman
creator: Diana van Heemst
creator: Joris Deelen
creator: Simon Mooijaart

Global Metabolomics Overview
type: Dataset
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T13:59:53+00:00
modified: 2024-11-07T14:00:36+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Eline Slagboom
creator: Joris Deelen
creator: Marian Beekman

FU Castor Balanstesten
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:31:19+00:00
modified: 2024-11-12T14:31:43+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Marian Beekman
creator: Eline Slagboom
creator: Diana van Heemst
creator: Joris Deelen
creator: Simon Mooijaart

LLS IOP3 Participant info
type: Dataset
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2022-07-22T15:09:50+00:00
modified: 2022-07-22T15:10:28+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Simon Mooijaart
creator: Marian Beekman
creator: Diana van Heemst
creator: Joris Deelen
creator: Eline Slagboom

LLS IOP2 Nightingale QL16-20
type: Dataset
description: From the group of 2,415 LLS PartnerOffspring that participated in the LLS between 2002 and 2006, 686 participants were examined for the second time between 2006 and 2008. In total 343 offspring and their partners (as couples living together) participated, with a mean age of 63 years. Of the 286 participants of the morning program, fasted blood was collected and serum/plasma was stored. Furthermore, skin replica’s and skin biopties were taken, from which viable fibroblasts were isolated and stored. The morning group was also subjected to an oral-glucose tolerance test. Of the 400 participants of the afternoon program, non-fasted blood was collected and serum/plasma and viable PBMCs were isolated and stored. The full blood was stimulated with LPS and cytokine levels were measured. From the majority of the total participants physical measures, DXA scan and standardized photographs of the face were taken, and all participants brought first morning void of urine which was stored.
issued: 2022-07-22T15:12:31+00:00
modified: 2022-08-09T15:05:46+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Diana van Heemst
creator: Joris Deelen
creator: Marian Beekman

LLS_IOP1_partoffs_Demography
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79) as population based controls. It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Partner Offspring consists of the 1671 offspring of nonagenarian siblings and their 744 partners from 421 families of whom we have physical measurements, biosamples, biomarkers, and questionnaire data. We followed this group of 2,415 middle-aged participants for their vital status till 2020, for their morbidity status till 2017.
issued: 2024-11-07T13:31:37+00:00
modified: 2024-11-07T13:32:54+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Joris Deelen
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Marian Beekman
creator: Diana van Heemst

LLS IOP3 Partoffs Apolipoprotein platform
type: Dataset
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2022-07-22T15:05:06+00:00
modified: 2022-07-22T15:05:56+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Joris Deelen
creator: Marian Beekman
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Eline Slagboom

Plasma endothelial markers
type: Dataset
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:46:33+00:00
modified: 2024-11-07T14:47:12+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Marian Beekman
creator: Joris Deelen
creator: Eline Slagboom

FU survey Fysieke activiteit (SQUASH)
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:46:49+00:00
modified: 2024-11-12T14:47:15+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Joris Deelen
creator: Eline Slagboom
creator: Marian Beekman

FU Castor Metingen handknijpkrachttest
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T13:27:39+00:00
modified: 2024-11-12T13:37:41+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Eline Slagboom
creator: Diana van Heemst
creator: Marian Beekman
creator: Joris Deelen
creator: Simon Mooijaart

SignalingLipids Metabolomics
type: Dataset
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:14:20+00:00
modified: 2024-11-07T14:15:35+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Eline Slagboom
creator: Marian Beekman
creator: Joris Deelen
creator: Diana van Heemst
creator: Simon Mooijaart

BEAT COVID Severity Score LUMC
type: Dataset
description: BEAT COVID Severity Score LUMC: Research laboratory data of LUMC BEAT COVID cohort. Prospective observational WMO study including 191 COVID-19 patients from April 2020 to March 2021. Over 400 different laboratory variables were measured, listed in the attached tables. Principle Investigator, Anna Roukens, LUCID. Website: https://w3id.org/lumc/lucid/beatcovid_severityscores
keyword: COVID-19
issued: 2024-02-04T00:00:00+00:00
modified: 2024-02-04T00:00:00+00:00
language: en
theme: HEAL
access rights: RESTRICTED
provenance: ProvenanceStatement
is referenced by: j.ebiom.2022.103957
is referenced by: j.isci.2022.105873
is referenced by: j.isci.2024.110374
is referenced by: j.lanmic.2024.07.005
is referenced by: s41590-021-01095-w
is referenced by: s41598-024-63586-8
is referenced by: journal.pone.0291212
is referenced by: cells11172743
contact point: Kind
  fn: Anna Roukens, Principle Investigator, Dept. LUCID, https://orcid.org/0000-0002-1397-0992
publisher: Leiden University Medical Center, the Netherlands
creator: Aswin Verhoeven
creator: Leendert A. Trouw
creator: Jacques J.M. van Dongen
creator: Michael R. del Prado
creator: Pieter S. Hiemstra
creator: Tom H.M. Ottenhoff
creator: M. Sesmu Arbous
creator: Anna Roukens, , Principal Investigator of the LUMC BEAT COVID group
creator: Anne M. van der Does
creator: Eric J. Snijder
creator: Simon P. Jochems
creator: Jeroen Eikenboom
creator: Simone A. Joosten
creator: Bernard M. van den Berg
creator: Thomas Hankemeier
creator: Frank J.T. Staal
creator: Manfred Wuhrer
creator: Meta Roestenberg
creator: David J. van Westerloo
creator: Mirjam H.M. Heemskerk
creator: Suzanne Cannegieter
creator: Judith Manniën
creator: Jelle J. Goeman
creator: Jeanette Wigbers
creator: Roula Tsonaka
creator: Leo G. Visser
creator: Henk J. van der Wijk
creator: Christa M. Cobbaert
creator: Marjolein Kikkert
creator: Robin C. van Wissen
creator: Lieke Lamont
creator: Annemieke Geluk
creator: Jacqueline J. Janse
creator: Maria Yazdanbakhsh
creator: Mariet C.W. Feltkamp
creator: Hermelijn H. Smits
creator: Jutte J.C. de Vries
creator: Cornelis H. Hokke
creator: T. Pongracz
creator: Martin Giera

FU Castor Metingen algemeen
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:49:57+00:00
modified: 2024-11-12T14:50:24+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Simon Mooijaart
creator: Marian Beekman
creator: Diana van Heemst
creator: Eline Slagboom
creator: Joris Deelen

LLS IOP3 Nightingale QL16-20
type: Dataset
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2022-07-22T15:08:02+00:00
modified: 2022-07-22T15:08:40+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Joris Deelen
creator: Diana van Heemst
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Marian Beekman

Cognition_questions
type: Dataset
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:22:43+00:00
modified: 2024-11-07T14:45:07+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Joris Deelen
creator: Marian Beekman
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Eline Slagboom

IOP2_Partoffs
type: DatasetSeries
description: From the group of 2,415 LLS PartnerOffspring that participated in the LLS between 2002 and 2006, 686 participants were examined for the second time between 2006 and 2008. In total 343 offspring and their partners (as couples living together) participated, with a mean age of 63 years. Of the 286 participants of the morning program, fasted blood was collected and serum/plasma was stored. Furthermore, skin replica’s and skin biopties were taken, from which viable fibroblasts were isolated and stored. The morning group was also subjected to an oral-glucose tolerance test. Of the 400 participants of the afternoon program, non-fasted blood was collected and serum/plasma and viable PBMCs were isolated and stored. The full blood was stimulated with LPS and cytokine levels were measured. From the majority of the total participants physical measures, DXA scan and standardized photographs of the face were taken, and all participants brought first morning void of urine which was stored.
issued: 2025-10-30T14:39:27.114788
modified: 2026-01-07T19:34:34.357576
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Marian Beekman
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Diana van Heemst
creator: Joris Deelen

FU survey Kwaliteit van leven (EQ-5D)
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T10:45:40+00:00
modified: 2024-11-12T10:49:39+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Joris Deelen
creator: Eline Slagboom
creator: Marian Beekman

Global Metabolomics Dictionary
type: Dataset
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T13:41:39+00:00
modified: 2024-11-07T13:54:27+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Diana van Heemst
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Joris Deelen
creator: Marian Beekman

FU Castor Medicatiegebruik
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:28:12+00:00
modified: 2024-11-12T14:28:31+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Joris Deelen
creator: Marian Beekman
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Eline Slagboom

Clinicalchemistry
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2024-11-07T13:37:47+00:00
modified: 2024-11-07T13:38:13+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Simon Mooijaart
creator: Marian Beekman
creator: Joris Deelen
creator: Diana van Heemst
creator: Eline Slagboom

LLS IOP2 Gripstrength
type: Dataset
description: From the group of 2,415 LLS PartnerOffspring that participated in the LLS between 2002 and 2006, 686 participants were examined for the second time between 2006 and 2008. In total 343 offspring and their partners (as couples living together) participated, with a mean age of 63 years. Of the 286 participants of the morning program, fasted blood was collected and serum/plasma was stored. Furthermore, skin replica’s and skin biopties were taken, from which viable fibroblasts were isolated and stored. The morning group was also subjected to an oral-glucose tolerance test. Of the 400 participants of the afternoon program, non-fasted blood was collected and serum/plasma and viable PBMCs were isolated and stored. The full blood was stimulated with LPS and cytokine levels were measured. From the majority of the total participants physical measures, DXA scan and standardized photographs of the face were taken, and all participants brought first morning void of urine which was stored.
issued: 2022-07-22T15:16:01+00:00
modified: 2022-07-22T15:16:25+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Marian Beekman
creator: Diana van Heemst
creator: Joris Deelen
creator: Simon Mooijaart
creator: Eline Slagboom

Castor Medische voorgeschiedenis CCI
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-07T15:24:48+00:00
modified: 2024-11-07T15:25:18+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Marian Beekman
creator: Eline Slagboom
creator: Joris Deelen

LLS IOP2 blood pressure
type: Dataset
description: From the group of 2,415 LLS PartnerOffspring that participated in the LLS between 2002 and 2006, 686 participants were examined for the second time between 2006 and 2008. In total 343 offspring and their partners (as couples living together) participated, with a mean age of 63 years. Of the 286 participants of the morning program, fasted blood was collected and serum/plasma was stored. Furthermore, skin replica’s and skin biopties were taken, from which viable fibroblasts were isolated and stored. The morning group was also subjected to an oral-glucose tolerance test. Of the 400 participants of the afternoon program, non-fasted blood was collected and serum/plasma and viable PBMCs were isolated and stored. The full blood was stimulated with LPS and cytokine levels were measured. From the majority of the total participants physical measures, DXA scan and standardized photographs of the face were taken, and all participants brought first morning void of urine which was stored.
issued: 2022-07-22T15:17:12+00:00
modified: 2022-07-22T15:17:37+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Eline Slagboom
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Joris Deelen
creator: Marian Beekman

FU Castor Metingen Longfunctie
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:18:42+00:00
modified: 2024-11-12T14:19:10+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Marian Beekman
creator: Simon Mooijaart
creator: Joris Deelen
creator: Diana van Heemst
creator: Eline Slagboom

FU_Nightingale_2024
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:32:45+00:00
modified: 2024-11-12T14:43:50+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Joris Deelen
creator: Marian Beekman
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Eline Slagboom

BEAT COVID Lab results LUMC
type: Dataset
description: BEAT COVID Lab results LUMC: Research laboratory data of LUMC BEAT COVID cohort. Prospective observational WMO study including 191 COVID-19 patients from April 2020 to March 2021. Over 400 different laboratory variables were measured, listed in the attached tables. Principle Investigator, Anna Roukens, LUCID. Website: https://w3id.org/lumc/lucid/beatcovid_labmeasurements
keyword: COVID-19
issued: 2024-02-04T00:00:00+00:00
modified: 2024-02-04T00:00:00+00:00
language: en
theme: HEAL
access rights: RESTRICTED
provenance: ProvenanceStatement
is referenced by: j.ebiom.2022.103957
is referenced by: j.isci.2022.105873
is referenced by: j.isci.2024.110374
is referenced by: j.lanmic.2024.07.005
is referenced by: s41590-021-01095-w
is referenced by: s41598-024-63586-8
is referenced by: journal.pone.0291212
is referenced by: cells11172743
contact point: Kind
  fn: Anna Roukens, Principle Investigator, Dept. LUCID, https://orcid.org/0000-0002-1397-0992
publisher: Leiden University Medical Center, the Netherlands
creator: Jutte J.C. de Vries
creator: Maria Yazdanbakhsh
creator: Roula Tsonaka
creator: Frank J.T. Staal
creator: Christa M. Cobbaert
creator: Aswin Verhoeven
creator: Suzanne Cannegieter
creator: Mariet C.W. Feltkamp
creator: Leendert A. Trouw
creator: Bernard M. van den Berg
creator: Hermelijn H. Smits
creator: Manfred Wuhrer
creator: Anna Roukens, , Principal Investigator of the LUMC BEAT COVID group
creator: Jacqueline J. Janse
creator: Mirjam H.M. Heemskerk
creator: Leo G. Visser
creator: Simone A. Joosten
creator: Pieter S. Hiemstra
creator: Simon P. Jochems
creator: Judith Manniën
creator: T. Pongracz
creator: Cornelis H. Hokke
creator: David J. van Westerloo
creator: Annemieke Geluk
creator: Tom H.M. Ottenhoff
creator: Jeanette Wigbers
creator: M. Sesmu Arbous
creator: Jacques J.M. van Dongen
creator: Jeroen Eikenboom
creator: Meta Roestenberg
creator: Martin Giera
creator: Lieke Lamont
creator: Robin C. van Wissen
creator: Henk J. van der Wijk
creator: Thomas Hankemeier
creator: Eric J. Snijder
creator: Marjolein Kikkert
creator: Anne M. van der Does
creator: Michael R. del Prado
creator: Jelle J. Goeman

Gut Microbiome related data
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2022-04-29T08:09:36+00:00
modified: 2022-06-13T12:01:18+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Marian Beekman
creator: Joris Deelen
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Eline Slagboom

LLS_IOP1_partoffs_Participant_info
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79) as population based controls. It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Partner Offspring consists of the 1671 offspring of nonagenarian siblings and their 744 partners from 421 families of whom we have physical measurements, biosamples, biomarkers, and questionnaire data. We followed this group of 2,415 middle-aged participants for their vital status till 2020, for their morbidity status till 2017.
issued: 2022-05-10T13:14:14+00:00
modified: 2022-06-13T12:03:19+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Marian Beekman
creator: Joris Deelen
creator: Diana van Heemst

Q1 FFQ Nevo2006
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:56:36+00:00
modified: 2024-11-12T14:57:00+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Marian Beekman
creator: Joris Deelen
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Eline Slagboom

Demography
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2022-04-29T08:16:26+00:00
modified: 2022-06-13T12:01:05+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Joris Deelen
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Diana van Heemst
creator: Marian Beekman

FU Castor Thuis biomateriaal
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:45:40+00:00
modified: 2024-11-12T14:46:05+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Marian Beekman
creator: Diana van Heemst
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Joris Deelen

LLS IOP2 BIA Body Composition
type: Dataset
description: From the group of 2,415 LLS PartnerOffspring that participated in the LLS between 2002 and 2006, 686 participants were examined for the second time between 2006 and 2008. In total 343 offspring and their partners (as couples living together) participated, with a mean age of 63 years. Of the 286 participants of the morning program, fasted blood was collected and serum/plasma was stored. Furthermore, skin replica’s and skin biopties were taken, from which viable fibroblasts were isolated and stored. The morning group was also subjected to an oral-glucose tolerance test. Of the 400 participants of the afternoon program, non-fasted blood was collected and serum/plasma and viable PBMCs were isolated and stored. The full blood was stimulated with LPS and cytokine levels were measured. From the majority of the total participants physical measures, DXA scan and standardized photographs of the face were taken, and all participants brought first morning void of urine which was stored.
issued: 2022-07-22T15:19:08+00:00
modified: 2022-07-22T15:19:38+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Joris Deelen
creator: Eline Slagboom
creator: Marian Beekman
creator: Diana van Heemst
creator: Simon Mooijaart

Q1 FFQ Food group key
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:53:44+00:00
modified: 2024-11-12T14:54:30+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Diana van Heemst
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Marian Beekman
creator: Joris Deelen

Castor Metingen ECG
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-07T15:23:41+00:00
modified: 2024-11-07T15:24:13+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Diana van Heemst
creator: Marian Beekman
creator: Simon Mooijaart
creator: Joris Deelen
creator: Eline Slagboom

LLS Follow Up study
type: DatasetSeries
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2025-10-30T14:40:24.332549
modified: 2026-01-07T19:34:11.242716
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Marian Beekman
creator: Eline Slagboom
creator: Joris Deelen

Visit measures
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2022-04-29T08:15:08+00:00
modified: 2022-06-13T12:03:59+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Marian Beekman
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Joris Deelen

Cell counts
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2022-04-29T08:14:14+00:00
modified: 2022-09-09T16:24:35+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Eline Slagboom
creator: Joris Deelen
creator: Marian Beekman
creator: Diana van Heemst
creator: Simon Mooijaart

Clinical Chemistry
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79) as population based controls. It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Partner Offspring consists of the 1671 offspring of nonagenarian siblings and their 744 partners from 421 families of whom we have physical measurements, biosamples, biomarkers, and questionnaire data. We followed this group of 2,415 middle-aged participants for their vital status till 2020, for their morbidity status till 2017.
issued: 2024-11-07T13:35:33+00:00
modified: 2024-11-07T13:36:41+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Diana van Heemst
creator: Joris Deelen
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Marian Beekman

Cellcounts
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79) as population based controls. It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Partner Offspring consists of the 1671 offspring of nonagenarian siblings and their 744 partners from 421 families of whom we have physical measurements, biosamples, biomarkers, and questionnaire data. We followed this group of 2,415 middle-aged participants for their vital status till 2020, for their morbidity status till 2017.
issued: 2022-05-10T12:29:13+00:00
modified: 2022-06-13T12:02:08+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Simon Mooijaart
creator: Joris Deelen
creator: Marian Beekman
creator: Diana van Heemst
creator: Eline Slagboom

Leiden NMR
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2022-04-29T08:13:18+00:00
modified: 2022-06-13T12:03:33+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Marian Beekman
creator: Joris Deelen
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Eline Slagboom

Q1 FFQ Fooditems
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:51:09+00:00
modified: 2024-11-12T14:52:12+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Joris Deelen
creator: Diana van Heemst
creator: Marian Beekman
creator: Eline Slagboom
creator: Simon Mooijaart

FU Castor Bloedafname
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:27:23+00:00
modified: 2024-11-12T14:27:46+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Joris Deelen
creator: Diana van Heemst
creator: Marian Beekman
creator: Simon Mooijaart
creator: Eline Slagboom

BEAT COVID Viral Ct
type: Dataset
description: BEAT COVID Viral Ct: Research laboratory data of LUMC BEAT COVID cohort. Prospective observational WMO study including 191 COVID-19 patients from April 2020 to March 2021. Over 400 different laboratory variables were measured, listed in the attached tables. Principle Investigator, Anna Roukens, LUCID. Website: https://w3id.org/lumc/lucid/beatcovid_viralct
keyword: COVID-19
issued: 2024-02-04T00:00:00+00:00
modified: 2024-02-04T00:00:00+00:00
language: en
theme: HEAL
access rights: RESTRICTED
provenance: ProvenanceStatement
is referenced by: j.ebiom.2022.103957
is referenced by: j.isci.2022.105873
is referenced by: j.isci.2024.110374
is referenced by: j.lanmic.2024.07.005
is referenced by: s41590-021-01095-w
is referenced by: s41598-024-63586-8
is referenced by: journal.pone.0291212
is referenced by: cells11172743
contact point: Kind
  fn: Anna Roukens, Principle Investigator, Dept. LUCID, https://orcid.org/0000-0002-1397-0992
publisher: Leiden University Medical Center, the Netherlands
creator: Leo G. Visser
creator: Hermelijn H. Smits
creator: Christa M. Cobbaert
creator: Anna Roukens, , Principal Investigator of the LUMC BEAT COVID group
creator: Aswin Verhoeven
creator: Robin C. van Wissen
creator: Martin Giera
creator: Simon P. Jochems
creator: Anne M. van der Does
creator: Marjolein Kikkert
creator: Pieter S. Hiemstra
creator: Bernard M. van den Berg
creator: Annemieke Geluk
creator: Frank J.T. Staal
creator: Jeanette Wigbers
creator: T. Pongracz
creator: Mirjam H.M. Heemskerk
creator: M. Sesmu Arbous
creator: Henk J. van der Wijk
creator: Manfred Wuhrer
creator: Michael R. del Prado
creator: Meta Roestenberg
creator: Suzanne Cannegieter
creator: Judith Manniën
creator: Jutte J.C. de Vries
creator: Mariet C.W. Feltkamp
creator: Leendert A. Trouw
creator: Jacques J.M. van Dongen
creator: Roula Tsonaka
creator: Eric J. Snijder
creator: Lieke Lamont
creator: Cornelis H. Hokke
creator: Jacqueline J. Janse
creator: Tom H.M. Ottenhoff
creator: David J. van Westerloo
creator: Jelle J. Goeman
creator: Simone A. Joosten
creator: Jeroen Eikenboom
creator: Thomas Hankemeier
creator: Maria Yazdanbakhsh

Q1 FFQ Macronutrients
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:55:12+00:00
modified: 2024-11-12T14:55:53+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Marian Beekman
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Joris Deelen

FU survey Alg vragenlijst LLS
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T10:51:13+00:00
modified: 2024-11-12T10:52:52+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Marian Beekman
creator: Joris Deelen
creator: Eline Slagboom

Participant information
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2022-04-28T15:40:58+00:00
modified: 2022-06-13T12:03:46+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Marian Beekman
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Joris Deelen
creator: Diana van Heemst

Nightingale
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2022-04-29T08:17:24+00:00
modified: 2022-06-13T12:01:38+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Marian Beekman
creator: Diana van Heemst
creator: Joris Deelen
creator: Simon Mooijaart
creator: Eline Slagboom

Survey Levensorientatie vragenlijst
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-07T15:26:03+00:00
modified: 2024-11-07T15:26:49+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Diana van Heemst
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Joris Deelen
creator: Marian Beekman

Q1 FFQ Foodgroups main
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:59:03+00:00
modified: 2024-11-12T14:59:25+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Marian Beekman
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Joris Deelen
creator: Eline Slagboom

IOP3_Partoffs
type: DatasetSeries
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2025-10-30T14:37:41.720505
modified: 2026-01-07T19:33:53.023818
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Marian Beekman
creator: Joris Deelen
creator: Diana van Heemst

LLS_IOP1_partoffs_LeidenNMR_Kimble
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79) as population based controls. It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Partner Offspring consists of the 1671 offspring of nonagenarian siblings and their 744 partners from 421 families of whom we have physical measurements, biosamples, biomarkers, and questionnaire data. We followed this group of 2,415 middle-aged participants for their vital status till 2020, for their morbidity status till 2017.
issued: 2022-05-10T13:13:42+00:00
modified: 2022-06-13T12:02:47+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Diana van Heemst
creator: Marian Beekman
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Joris Deelen

SignalingLipids Dictionary
type: Dataset
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:11:04+00:00
modified: 2024-11-07T14:11:40+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Marian Beekman
creator: Joris Deelen
creator: Eline Slagboom

LLS Questionnaire 1
type: DatasetSeries
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2025-10-30T14:39:40.535847
modified: 2026-01-07T19:33:49.573403
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Joris Deelen
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Marian Beekman
creator: Diana van Heemst

MRI Data
type: Dataset
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:48:28+00:00
modified: 2024-11-07T14:48:59+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Marian Beekman
creator: Diana van Heemst
creator: Eline Slagboom
creator: Joris Deelen
creator: Simon Mooijaart

Castor Cognitietesten
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-07T14:51:25+00:00
modified: 2024-11-07T14:52:03+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Joris Deelen
creator: Simon Mooijaart
creator: Marian Beekman
creator: Diana van Heemst
creator: Eline Slagboom

LLS_IOP1_Partoffs_Nightingale
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79) as population based controls. It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Partner Offspring consists of the 1671 offspring of nonagenarian siblings and their 744 partners from 421 families of whom we have physical measurements, biosamples, biomarkers, and questionnaire data. We followed this group of 2,415 middle-aged participants for their vital status till 2020, for their morbidity status till 2017.
issued: 2022-05-10T13:12:37+00:00
modified: 2022-06-13T12:03:05+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Joris Deelen
creator: Eline Slagboom
creator: Marian Beekman

LLS IOP2 Participant info
type: Dataset
description: From the group of 2,415 LLS PartnerOffspring that participated in the LLS between 2002 and 2006, 686 participants were examined for the second time between 2006 and 2008. In total 343 offspring and their partners (as couples living together) participated, with a mean age of 63 years. Of the 286 participants of the morning program, fasted blood was collected and serum/plasma was stored. Furthermore, skin replica’s and skin biopties were taken, from which viable fibroblasts were isolated and stored. The morning group was also subjected to an oral-glucose tolerance test. Of the 400 participants of the afternoon program, non-fasted blood was collected and serum/plasma and viable PBMCs were isolated and stored. The full blood was stimulated with LPS and cytokine levels were measured. From the majority of the total participants physical measures, DXA scan and standardized photographs of the face were taken, and all participants brought first morning void of urine which was stored.
issued: 2022-07-22T15:18:08+00:00
modified: 2022-07-22T15:18:37+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Eline Slagboom
creator: Diana van Heemst
creator: Joris Deelen
creator: Marian Beekman
creator: Simon Mooijaart

FU Castor Metingen BIA meting
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:47:47+00:00
modified: 2024-11-12T14:48:36+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Diana van Heemst
creator: Marian Beekman
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Joris Deelen

Q1_FFQ_Aminoacids
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:59:52+00:00
modified: 2024-11-12T15:00:15+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Joris Deelen
creator: Diana van Heemst
creator: Marian Beekman
creator: Simon Mooijaart
creator: Eline Slagboom

IOP1_Partoffs
type: DatasetSeries
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79) as population based controls. It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Partner Offspring consists of the 1671 offspring of nonagenarian siblings and their 744 partners from 421 families of whom we have physical measurements, biosamples, biomarkers, and questionnaire data. We followed this group of 2,415 middle-aged participants for their vital status till 2020, for their morbidity status till 2017.
issued: 2025-10-30T14:39:05.634673
modified: 2026-01-07T19:33:41.058351
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Joris Deelen
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Marian Beekman
creator: Eline Slagboom

FU Castor Scores questionair toeval
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:26:19+00:00
modified: 2024-11-12T14:27:00+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Eline Slagboom
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Joris Deelen
creator: Marian Beekman

IGF axis
type: Dataset
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:21:23+00:00
modified: 2024-11-07T14:21:49+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Diana van Heemst
creator: Marian Beekman
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Joris Deelen

LLS_IOP3_OLINKcardiomatebolic_samples
type: Dataset
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-02-09T08:29:24+00:00
modified: 2024-02-09T08:29:50+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Joris Deelen
creator: Eline Slagboom
creator: Marian Beekman

FU Castor Metingen bloeddruk
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T13:48:58+00:00
modified: 2024-11-12T14:17:04+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Eline Slagboom
creator: Marian Beekman
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Joris Deelen

FU survey Fysieke functie ADL IADL
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:44:26+00:00
modified: 2024-11-12T14:45:08+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Diana van Heemst
creator: Marian Beekman
creator: Eline Slagboom
creator: Joris Deelen
creator: Simon Mooijaart

Thyroid measures
type: Dataset
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:49:46+00:00
modified: 2024-11-07T14:50:15+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Marian Beekman
creator: Diana van Heemst
creator: Joris Deelen
creator: Simon Mooijaart
creator: Eline Slagboom

LLS IOP2 Clinical chemistry
type: Dataset
description: From the group of 2,415 LLS PartnerOffspring that participated in the LLS between 2002 and 2006, 686 participants were examined for the second time between 2006 and 2008. In total 343 offspring and their partners (as couples living together) participated, with a mean age of 63 years. Of the 286 participants of the morning program, fasted blood was collected and serum/plasma was stored. Furthermore, skin replica’s and skin biopties were taken, from which viable fibroblasts were isolated and stored. The morning group was also subjected to an oral-glucose tolerance test. Of the 400 participants of the afternoon program, non-fasted blood was collected and serum/plasma and viable PBMCs were isolated and stored. The full blood was stimulated with LPS and cytokine levels were measured. From the majority of the total participants physical measures, DXA scan and standardized photographs of the face were taken, and all participants brought first morning void of urine which was stored.
issued: 2022-07-22T15:14:19+00:00
modified: 2022-07-22T15:15:05+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Joris Deelen
creator: Marian Beekman
creator: Eline Slagboom
creator: Diana van Heemst
creator: Simon Mooijaart

LLS_IOP3_OLINKcardiomatebolic_measures
type: Dataset
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-02-09T08:26:50+00:00
modified: 2024-02-09T08:27:25+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Marian Beekman
creator: Joris Deelen
creator: Eline Slagboom

Q1 FFQ key food groups 20200911
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T15:00:58+00:00
modified: 2024-11-12T15:01:33+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Marian Beekman
creator: Simon Mooijaart
creator: Joris Deelen
creator: Eline Slagboom
creator: Diana van Heemst

Q1 FFQ Foodgroups sub
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:58:07+00:00
modified: 2024-11-12T14:58:32+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Eline Slagboom
creator: Marian Beekman
creator: Simon Mooijaart
creator: Joris Deelen
creator: Diana van Heemst

IOP1_Sibs
type: DatasetSeries
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2025-10-30T14:39:11.882072
modified: 2026-01-07T19:33:28.046511
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Marian Beekman
creator: Joris Deelen
creator: Diana van Heemst

FU Castor Welkom
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:49:04+00:00
modified: 2024-11-12T14:49:29+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Joris Deelen
creator: Eline Slagboom
creator: Marian Beekman

FU survey Voedingsvragenlijst (FFQ)
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:30:27+00:00
modified: 2024-11-12T14:30:55+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Simon Mooijaart
creator: Marian Beekman
creator: Eline Slagboom
creator: Diana van Heemst
creator: Joris Deelen

FU survey Fysieke activeit (SQUASH) OUD
type: Dataset
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T10:43:54+00:00
modified: 2024-11-12T10:44:55+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Marian Beekman
creator: Eline Slagboom
creator: Joris Deelen

BEAT COVID Info LUMC
type: Dataset
description: BEAT COVID Info LUMC: Research laboratory data of LUMC BEAT COVID cohort. Prospective observational WMO study including 191 COVID-19 patients from April 2020 to March 2021. Over 400 different laboratory variables were measured, listed in the attached tables. Principle Investigator, Anna Roukens, LUCID. Website: https://w3id.org/lumc/lucid/beatcovid_info
keyword: COVID-19
issued: 2024-02-04T00:00:00+00:00
modified: 2024-02-04T00:00:00+00:00
language: en
theme: HEAL
access rights: RESTRICTED
provenance: ProvenanceStatement
is referenced by: j.ebiom.2022.103957
is referenced by: j.isci.2022.105873
is referenced by: j.isci.2024.110374
is referenced by: j.lanmic.2024.07.005
is referenced by: s41590-021-01095-w
is referenced by: s41598-024-63586-8
is referenced by: journal.pone.0291212
is referenced by: cells11172743
contact point: Kind
  fn: Anna Roukens, Principle Investigator, Dept. LUCID, https://orcid.org/0000-0002-1397-0992
publisher: Leiden University Medical Center, the Netherlands
creator: Marjolein Kikkert
creator: Anne M. van der Does
creator: Simon P. Jochems
creator: David J. van Westerloo
creator: Aswin Verhoeven
creator: Judith Manniën
creator: Michael R. del Prado
creator: Hermelijn H. Smits
creator: Cornelis H. Hokke
creator: Jacques J.M. van Dongen
creator: Lieke Lamont
creator: Frank J.T. Staal
creator: Annemieke Geluk
creator: Henk J. van der Wijk
creator: Mirjam H.M. Heemskerk
creator: T. Pongracz
creator: Jelle J. Goeman
creator: Martin Giera
creator: Pieter S. Hiemstra
creator: Jacqueline J. Janse
creator: Bernard M. van den Berg
creator: Leo G. Visser
creator: Suzanne Cannegieter
creator: Maria Yazdanbakhsh
creator: Thomas Hankemeier
creator: Jeroen Eikenboom
creator: Meta Roestenberg
creator: Robin C. van Wissen
creator: Roula Tsonaka
creator: Jutte J.C. de Vries
creator: Tom H.M. Ottenhoff
creator: Mariet C.W. Feltkamp
creator: Anna Roukens, , Principal Investigator of the LUMC BEAT COVID group
creator: Jeanette Wigbers
creator: M. Sesmu Arbous
creator: Leendert A. Trouw
creator: Christa M. Cobbaert
creator: Manfred Wuhrer
creator: Simone A. Joosten
creator: Eric J. Snijder

Plasma Amyloid markers
type: Dataset
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:19:37+00:00
modified: 2024-11-07T14:20:21+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
publisher: Leiden University Medical Center
creator: Eline Slagboom
creator: Joris Deelen
creator: Diana van Heemst
creator: Marian Beekman
creator: Simon Mooijaart

COMODULATE Lab results LUMC
type: Dataset
description: COMODULATE Lab results LUMC: Research laboratory data of the LUMC COMODULATE cohort. Retrospective observational non-WMO study including COVID-19 and Influenza patients with and without ARDS from 2019 to 2024. Host transcriptomics and inflammatory proteomics variables were measured in respiratory samples. Principle Investigator, Jutte JC de Vries, LUCID. Website: https://w3id.org/lumc/lucid/comodulate_labmeasurements
keyword: COVID-19
keyword: Influenza
keyword: transcriptomics
issued: 2025-04-04T00:00:00+00:00
modified: 2025-04-04T00:00:00+00:00
language: en
theme: HEAL
access rights: RESTRICTED
provenance: ProvenanceStatement
is referenced by: personalised-targeted-immunomodulation-patients-ards-related-covid19-and-future-pandemic
contact point: Kind
  fn: Jutte J.C. de Vries, Principle Investigator, Dept. LUCID, https://orcid.org/0000-0003-2530-6260
publisher: Leiden University Medical Center, the Netherlands
creator: Simon P. Jochems
creator: Jutte J.C. de Vries, Principal Investigator

EuCanImage_GUMED_UC8
type: Dataset
description: Within the EuCanImage project (https://eucanimage.eu/), imaging datasets are collected from multiple sites to facilitate the use of AI for cancer research. The BMIA XNAT will be used as main image data storage platform for centralized storage. As first usecase, breast cancer was identified, for which the first datasets will be collected from the University of Barcelona. The data will first be available to partners within the consortium, but will potentially be publicly released
issued: 2024-12-05T17:21:09+00:00
modified: 2024-12-05T17:21:09+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Example Data Management office
  has UID: example.com
publisher: Example publisher list
creator: Ivan Bocharov
creator: Dr. Martijn Starmans

AILS
type: Dataset
description: Retrospective analysis of atypical iso intense lesions after Primovist injection
issued: 2024-12-09T10:47:27+00:00
modified: 2024-12-09T10:47:27+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Health-RI servicedesk
  has UID: example.com
publisher: Health-RI
creator: Maarten Thomeer

Brain_MRI_WML_ERASMUS
type: Dataset
description: This collection will include brain MRI scans on which the amount of white matter lesions (WML) will be quantified.
issued: 2024-12-05T20:15:02+00:00
modified: 2024-12-05T20:15:02+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Health-RI servicedesk
  has UID: example.com
publisher: Health-RI
creator: prof.dr. Aad van der Lugt

CIRGUIDANCERadiomics Zuyderland Ziekenhuis
type: Dataset
description: In this study, we aim to use a non-invasive radiomics alternative to predict the lymph node stage in patients with non-metastatic muscle-invasive bladder cancer. To this end, we will use the already gathered computed tomography (CT) data from the previously performed multicenter CIRGUIDANCE study. We would like to use the Trait XNAT to share the data among the hospitals.
issued: 2024-12-05T20:15:03+00:00
modified: 2024-12-05T20:15:03+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Health-RI servicedesk
  has UID: example.com
publisher: Health-RI
creator: Dr. Martijn Starmans
creator: Anouk de Jong

Nivel Primary Care General Practices 2012
type: Dataset
description: Electronic health record data from general practices spread throughout the Netherlands. General practice care comprises regular healthcare provision during normal practice hours, excluding out-of-hours primary care, emergency care and hospital admissions
keyword: EHR
keyword: Electronic Health Records EHR
keyword: Primary Care
keyword: Routine Healthcare Data
issued: 2025-11-04T16:23:24.322884
modified: 2026-01-07T19:31:47.146175
language: en
theme: HEAL
access rights: NON PUBLIC
provenance: ProvenanceStatement
applicable legislation: oj
contact point: Kind
  fn: Leontien Korteweg
publisher: Nivel
creator: Nivel

DEFENCE: Determination and Evaluation of the Frequency and Effects of myocardial damage iN patients with a SARS-CoV-2 infEction
type: Dataset
description: DEFENCE: Determination and Evaluation of the Frequency and Effects of myocardial damage iN patients with a SARS-CoV-2 infEction
landing page: https://covid19initiatives.health-ri.nl/p/Project/27866022694497953
keyword: Acute myocardial infarction
keyword: COVID-19
keyword: COVID-19 patient grouping
keyword: COVID-19 phase
keyword: Cardiac arrhythmia unspecified
keyword: Cerebrovascular diseases I60-I69
keyword: GP care
keyword: Heart failure
keyword: Myocarditis unspecified
keyword: home care
keyword: hospital care
keyword: human disease
keyword: national
issued: 2021-09-13T07:15:23+00:00
modified: 2021-09-20T11:43:48+00:00
language: en
theme: I21
theme: I49.9
theme: I50
theme: I51.4
theme: I60-I69
theme: U07.1
theme: http://purl.org/zonmw/covid19/10007
theme: http://purl.org/zonmw/covid19/10010
theme: http://purl.org/zonmw/covid19/10012
theme: http://purl.org/zonmw/covid19/10014
theme: http://purl.org/zonmw/covid19/10033
theme: http://purl.org/zonmw/covid19/10091
theme: http://purl.org/zonmw/generic/10095
temporal: PeriodOfTime
  start date: 2021-10-01T00:00:00+00:00
  end date: 2023-10-01T00:00:00+00:00
provenance: ProvenanceStatement
contact point: Kind
  fn: Folkert W. Asselbergs
  has UID: https://orcid.org/0000-0002-1692-8669
publisher: Erik van Iperen
creator: Erik van Iperen

CVON MIND AF
type: Dataset
description: Brein MRIs van patiënten met permanent AF
issued: 2024-12-05T20:15:03+00:00
modified: 2024-12-05T20:15:03+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Health-RI servicedesk
  has UID: example.com
publisher: Health-RI
creator: Don van Velzen
creator: Cornelis Allaart
creator: Eelco Soeteman
creator: Annemarie Scholman

EXCEPTIUS : Exceptional powers in time of Sars -CoV-2
type: Dataset
description: EXCEPTIUS : Exceptional powers in time of Sars -CoV-2
landing page: https://covid19initiatives.health-ri.nl/p/Project/27866022694506515
keyword: COVID-19 phase
keyword: international
keyword: national
keyword: national care public health measures
keyword: other
keyword: regional
keyword: target group of policy interventions
issued: 2023-03-15T08:54:12+00:00
modified: 2023-03-15T08:54:21+00:00
language: en
theme: http://purl.org/zonmw/covid19/10006
theme: http://purl.org/zonmw/covid19/10007
theme: http://purl.org/zonmw/covid19/10008
theme: http://purl.org/zonmw/covid19/10033
theme: http://purl.org/zonmw/covid19/10098
theme: http://purl.org/zonmw/generic/10006
temporal: PeriodOfTime
  start date: 2020-09-07T00:00:00+00:00
  end date: 2022-09-07T00:00:00+00:00
provenance: ProvenanceStatement
contact point: Kind
  fn: Clara Egger
  has UID: 0000-0001-7293-111X
publisher: Clara Egger
creator: Clara Egger

BIGR[eye] EMC
type: Dataset
description: Data collected within the eye research group of the Biomedical Imaging Group Rotterdam, Erasmus MC
issued: 2024-12-05T20:15:02+00:00
modified: 2024-12-05T20:15:02+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Health-RI servicedesk
  has UID: example.com
publisher: Health-RI
creator: Dr. Luisa Sanchez Brea
creator: Dr. Danilo Andrade De Jesus

EGD
type: Dataset
description: FOR ACCESS TO THE DATASET: Do not request an account directly through the XNAT portal. If you would like to access the dataset please send an email to: servicedesk@health-ri.nl You will then be asked to sign the data usage agreement, and an account will be created for you. ACCESS REQUESTS DIRECTLY THROUGH THE XNAT PORTAL WILL NOT BE CONSIDERED. The Erasmus Glioma Database (EGD) is a collection of 774 patients with glioma. For this patients pre-operative imaging, genetic and histological data, and tumor segmentations are available. See the license for all conditions: check the file 'data_license.pdf' at Resources > PROJECT_DATA Some scans might have a poor image quality or errors due to registration issues. We have marked this scans as 'unacceptable' scan quality. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 952103
issued: 2024-12-05T17:21:07+00:00
modified: 2024-12-05T17:21:07+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Example Data Management office
  has UID: example.com
publisher: Example publisher list
creator: Dr. ir. Stefan Klein
creator: Sebastian van der Voort
creator: Marion Smits

https://fdp-acc.healthdata.nl/dataset/8561b0d4-10b8-43ac-8d60-1fdb522adb40
type: Dataset
title: Waarderend onderzoeken en ontwikkelen: leidt de toepassing van deze interventie in de teams van de Stichting Jeugdgezondheidszorg Zuid-Holland West tot het versterken en waarborgen van de mentale vitaliteit van medewerkers?
description: Waarderend onderzoeken en ontwikkelen: leidt de toepassing van deze interventie in de teams van de Stichting Jeugdgezondheidszorg Zuid-Holland West tot het versterken en waarborgen van de mentale vitaliteit van medewerkers?
landing page: https://covid19initiatives.health-ri.nl/p/Project/27866022694561626
issued: 2023-12-18T14:39:08+00:00
modified: 2023-12-18T14:45:36+00:00
language: en
theme: U07.1
temporal: PeriodOfTime
  start date: 2022-12-15T00:00:00+00:00
  end date: 2023-12-15T00:00:00+00:00
provenance: ProvenanceStatement
contact point: Kind
  fn: Martijn Hendriks
  has UID: https://orcid.org/0000-0002-9528-0871
publisher: Martijn Hendriks
creator: Martijn Hendriks

Timing and sequence of vaccination against COVID-19 and Influenza
type: Dataset
description: Timing and sequence of vaccination against COVID-19 and Influenza
landing page: https://covid19initiatives.health-ri.nl/p/Project/27866022694497950
keyword: COVID-19 phase
keyword: Codes for special purposes U00-U85
keyword: GP care
keyword: human disease
keyword: national
keyword: people by age
issued: 2021-09-09T08:32:43+00:00
modified: 2021-09-09T12:17:19+00:00
language: en
theme: U00-U85
theme: http://purl.org/zonmw/covid19/10007
theme: http://purl.org/zonmw/covid19/10012
theme: http://purl.org/zonmw/covid19/10033
theme: http://purl.org/zonmw/covid19/10038
theme: http://purl.org/zonmw/generic/10095
temporal: PeriodOfTime
  start date: 2021-10-01T00:00:00+00:00
  end date: 2022-09-01T00:00:00+00:00
provenance: ProvenanceStatement
contact point: Kind
  fn: Josephine van de Maat
  has UID: https://orcid.org/0000-0001-7351-4596
publisher: Elisabeth Dulfer
creator: Elisabeth Dulfer

Lanadelumab for Treatment of COVID-19 Disease
type: Dataset
description: Lanadelumab for Treatment of COVID-19 Disease
landing page: https://covid19initiatives.health-ri.nl/p/Project/27866022694542657
keyword: COVID-19 U07.1
keyword: COVID-19 patient grouping
keyword: COVID-19 phase
keyword: health care phase
keyword: hospital care
keyword: human disease
keyword: national
keyword: other
issued: 2023-09-10T20:18:50+00:00
modified: 2023-09-11T08:21:06+00:00
language: en
theme: http://purl.org/zonmw/covid19/10007
theme: http://purl.org/zonmw/covid19/10014
theme: http://purl.org/zonmw/covid19/10018
theme: http://purl.org/zonmw/covid19/10033
theme: http://purl.org/zonmw/covid19/10091
theme: http://purl.org/zonmw/generic/10006
theme: http://purl.org/zonmw/generic/10095
temporal: PeriodOfTime
  start date: 2020-09-05T00:00:00+00:00
  end date: 2021-09-05T00:00:00+00:00
provenance: ProvenanceStatement
contact point: Kind
  fn: Frank van de Veerdonk
  has UID: https://orcid.org/0000-0002-1121-4894
publisher: Job Engel
creator: Job Engel

Healthcare utilization in primary care during the corona pandemic: a nation-wide population-based study from a patient and healthcare provider perspective
type: Dataset
description: Healthcare utilization in primary care during the corona pandemic: a nation-wide population-based study from a patient and healthcare provider perspective
landing page: https://covid19initiatives.health-ri.nl/p/Project/27866022694498246
keyword: COVID-19 phase
keyword: Cerebral infarction
keyword: GP care
keyword: human disease
keyword: national
keyword: people by age
issued: 2021-09-29T14:15:22+00:00
modified: 2021-09-29T14:28:20+00:00
language: en
theme: I63
theme: http://purl.org/zonmw/covid19/10007
theme: http://purl.org/zonmw/covid19/10012
theme: http://purl.org/zonmw/covid19/10033
theme: http://purl.org/zonmw/covid19/10038
theme: http://purl.org/zonmw/generic/10095
temporal: PeriodOfTime
  start date: 2020-09-01T00:00:00+00:00
  end date: 2022-03-01T00:00:00+00:00
provenance: ProvenanceStatement
contact point: Kind
  fn: Evelien de Schepper
  has UID: https://orcid.org/0000-0002-1896-6343
publisher: Evelien de Schepper
creator: Evelien de Schepper

AFRICAI_MICCAI2024_CTSpine1K
type: Dataset
description: Collection of data from the MICCAI 2024 CTSpine1K Dataset as part of the EuCanImage sponsored AFRICAI repository. In this repository, we introduce a large-scale spine CT dataset called CTSpine1K, curated from multiple sources for vertebra segmentation, which contains 1,005 CT volumes with over 500,000 labeled vertebrae slices and 11,172 vertebrae belonging to different spinal conditions. The data within this work is licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (CC BY-NC-SA 4.0) If you use our dataset, please cite our paper: Yang Deng, Ce Wang, Yuan Hui, et al. CtSpine1k: A large-scale dataset for spinal vertebrae segmentation in computed tomography. arXiv preprint arXiv:2105.14711 (2021).
keyword: Dataset
keyword: Image
keyword: Medical
keyword: Segmentation
keyword: Spine
issued: 2024-12-09T10:47:27+00:00
modified: 2024-12-09T10:47:27+00:00
language: en
theme: HEAL
provenance: ProvenanceStatement
contact point: Kind
  fn: Health-RI servicedesk
  has UID: example.com
publisher: Health-RI
creator: Yang Deng

Caging the dragon: translational approach to unravel and prevent COVID-19 associated thrombosis (10430012010004)
type: Dataset
description: Caging the dragon: translational approach to unravel and prevent COVID-19 associated thrombosis (10430012010004)
landing page: https://covid19initiatives.health-ri.nl/p/Project/27866022694514811
keyword: COVID-19 patient grouping
keyword: COVID-19 phase
keyword: COVID-19 vaccination grouping
keyword: Diseases of veins lymphatic vessels and lymph nodes not elsewhere classified I80-I89
keyword: Pulmonary heart disease and diseases of pulmonary circulation I26-I28
keyword: health care phase
keyword: home care
keyword: hospital care
keyword: human disease
keyword: local
keyword: national
keyword: nursing home care
keyword: other
keyword: outpatient care
keyword: people by age
keyword: regional
keyword: residential care
issued: 2023-05-23T14:39:28+00:00
modified: 2023-05-23T14:41:08+00:00
language: en
theme: I26-I28
theme: I80-I89
theme: http://purl.org/zonmw/covid19/10005
theme: http://purl.org/zonmw/covid19/10006
theme: http://purl.org/zonmw/covid19/10007
theme: http://purl.org/zonmw/covid19/10010
theme: http://purl.org/zonmw/covid19/10013
theme: http://purl.org/zonmw/covid19/10014
theme: http://purl.org/zonmw/covid19/10016
theme: http://purl.org/zonmw/covid19/10017
theme: http://purl.org/zonmw/covid19/10018
theme: http://purl.org/zonmw/covid19/10033
theme: http://purl.org/zonmw/covid19/10038
theme: http://purl.org/zonmw/covid19/10091
theme: http://purl.org/zonmw/covid19/10220
theme: http://purl.org/zonmw/generic/10006
theme: http://purl.org/zonmw/generic/10095
temporal: PeriodOfTime
  start date: 2020-05-01T00:00:00+00:00
  end date: 2024-01-01T00:00:00+00:00
provenance: ProvenanceStatement
contact point: Kind
  fn: Marieke Kruip
  has UID: https://orcid.org/0000-0002-0265-4871
publisher: Chantal Chantal
creator: Eva Kempers
creator: Chantal Visser

Een onverwachte valse start op de arbeidsmarkt
type: Dataset
description: Een onverwachte valse start op de arbeidsmarkt
landing page: https://covid19initiatives.health-ri.nl/p/Project/27866022694506050
keyword: COVID-19
keyword: COVID-19 phase
keyword: Effects COVID on participation
keyword: human disease
keyword: national
keyword: other
keyword: people by education
issued: 2023-03-10T12:53:20+00:00
modified: 2023-03-10T14:29:18+00:00
language: en
theme: http://purl.org/zonmw/covid19/10007
theme: http://purl.org/zonmw/covid19/10033
theme: http://purl.org/zonmw/covid19/10060
theme: http://purl.org/zonmw/generic/10006
theme: http://purl.org/zonmw/generic/10095
temporal: PeriodOfTime
  start date: 2020-09-01T00:00:00+00:00
  end date: 2022-12-31T00:00:00+00:00
provenance: ProvenanceStatement
contact point: Kind
  fn: Bas ter Weel
  has UID: https://orcid.org/0000-0001-8446-7457
publisher: Bas ter Weel
creator: Bas ter Weel

Economische Veerkracht van Regio's
type: Dataset
description: Economische Veerkracht van Regio's
landing page: https://covid19initiatives.health-ri.nl/p/Project/27866022694516799
keyword: COVID-19 phase
keyword: human disease
keyword: other
keyword: regional
issued: 2023-05-30T11:16:43+00:00
modified: 2024-01-25T08:19:33+00:00
language: en
theme: http://purl.org/zonmw/covid19/10006
theme: http://purl.org/zonmw/covid19/10033
theme: http://purl.org/zonmw/generic/10006
theme: http://purl.org/zonmw/generic/10095
temporal: PeriodOfTime
  start date: 2020-10-15T00:00:00+00:00
  end date: 2023-01-15T00:00:00+00:00
provenance: ProvenanceStatement
contact point: Kind
  fn: Erik Stam
  has UID: https://orcid.org/0000-0001-9827-0516
publisher: Erik Stam
creator: Erik Stam

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