Q1 FFQ Nevo2006
type: Dataset
creator: Eline Slagboom
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Joris Deelen
creator: Marian Beekman
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:56:36+00:00
language: en
modified: 2024-11-12T14:57:00+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Q1 FFQ Foodgroups main
type: Dataset
creator: Joris Deelen
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Marian Beekman
creator: Eline Slagboom
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:59:03+00:00
language: en
modified: 2024-11-12T14:59:25+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Global Metabolomics
type: Dataset
creator: Eline Slagboom
creator: Marian Beekman
creator: Diana van Heemst
creator: Joris Deelen
creator: Simon Mooijaart
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:07:22+00:00
language: en
modified: 2024-11-07T14:09:32+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

LLS_IOP1_partoffs_Participant_info
type: Dataset
creator: Marian Beekman
creator: Eline Slagboom
creator: Diana van Heemst
creator: Joris Deelen
creator: Simon Mooijaart
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79) as population based controls. It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Partner Offspring consists of the 1671 offspring of nonagenarian siblings and their 744 partners from 421 families of whom we have physical measurements, biosamples, biomarkers, and questionnaire data. We followed this group of 2,415 middle-aged participants for their vital status till 2020, for their morbidity status till 2017.
issued: 2022-05-10T13:14:14+00:00
language: en
modified: 2022-06-13T12:03:19+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

LLS IOP3 Participant info
type: Dataset
creator: Joris Deelen
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Marian Beekman
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2022-07-22T15:09:50+00:00
language: en
modified: 2022-07-22T15:10:28+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Global Metabolomics Dictionary
type: Dataset
creator: Marian Beekman
creator: Joris Deelen
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Diana van Heemst
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T13:41:39+00:00
language: en
modified: 2024-11-07T13:54:27+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

LLS_IOP1_Partoffs_Nightingale
type: Dataset
creator: Marian Beekman
creator: Joris Deelen
creator: Eline Slagboom
creator: Diana van Heemst
creator: Simon Mooijaart
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79) as population based controls. It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Partner Offspring consists of the 1671 offspring of nonagenarian siblings and their 744 partners from 421 families of whom we have physical measurements, biosamples, biomarkers, and questionnaire data. We followed this group of 2,415 middle-aged participants for their vital status till 2020, for their morbidity status till 2017.
issued: 2022-05-10T13:12:37+00:00
language: en
modified: 2022-06-13T12:03:05+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

CKAN
type: Catalog
language: en
modified: 2026-01-07T19:34:58.399870

BEAT COVID Viral Ct
type: Dataset
access rights: RESTRICTED
creator: Eric J. Snijder
creator: Simone A. Joosten
creator: Anna Roukens, , Principal Investigator of the LUMC BEAT COVID group
creator: Leendert A. Trouw
creator: Aswin Verhoeven
creator: Anne M. van der Does
creator: Hermelijn H. Smits
creator: Leo G. Visser
creator: Cornelis H. Hokke
creator: Maria Yazdanbakhsh
creator: Judith Manniën
creator: Pieter S. Hiemstra
creator: Robin C. van Wissen
creator: Suzanne Cannegieter
creator: Bernard M. van den Berg
creator: T. Pongracz
creator: Thomas Hankemeier
creator: Manfred Wuhrer
creator: Mirjam H.M. Heemskerk
creator: Tom H.M. Ottenhoff
creator: Michael R. del Prado
creator: Marjolein Kikkert
creator: Jelle J. Goeman
creator: Christa M. Cobbaert
creator: Frank J.T. Staal
creator: M. Sesmu Arbous
creator: Henk J. van der Wijk
creator: Lieke Lamont
creator: Jacqueline J. Janse
creator: Martin Giera
creator: Jeanette Wigbers
creator: Jutte J.C. de Vries
creator: David J. van Westerloo
creator: Mariet C.W. Feltkamp
creator: Annemieke Geluk
creator: Jacques J.M. van Dongen
creator: Jeroen Eikenboom
creator: Roula Tsonaka
creator: Simon P. Jochems
creator: Meta Roestenberg
description: BEAT COVID Viral Ct: Research laboratory data of LUMC BEAT COVID cohort. Prospective observational WMO study including 191 COVID-19 patients from April 2020 to March 2021. Over 400 different laboratory variables were measured, listed in the attached tables. Principle Investigator, Anna Roukens, LUCID. Website: https://w3id.org/lumc/lucid/beatcovid_viralct
is referenced by: j.isci.2024.110374
is referenced by: s41590-021-01095-w
is referenced by: s41598-024-63586-8
is referenced by: j.isci.2022.105873
is referenced by: j.ebiom.2022.103957
is referenced by: j.lanmic.2024.07.005
is referenced by: cells11172743
is referenced by: journal.pone.0291212
issued: 2024-02-04T00:00:00+00:00
language: en
modified: 2024-02-04T00:00:00+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center, the Netherlands
contact point: Kind
  fn: Anna Roukens, Principle Investigator, Dept. LUCID, https://orcid.org/0000-0002-1397-0992
keyword: COVID-19
theme: HEAL

Q1 FFQ Foodgroups sub
type: Dataset
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Marian Beekman
creator: Joris Deelen
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:58:07+00:00
language: en
modified: 2024-11-12T14:58:32+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

LLS_IOP3_OLINKcardiomatebolic_samples
type: Dataset
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Joris Deelen
creator: Marian Beekman
creator: Eline Slagboom
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-02-09T08:29:24+00:00
language: en
modified: 2024-02-09T08:29:50+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Economische Veerkracht van Regio's
type: Dataset
creator: Erik Stam
description: Economische Veerkracht van Regio's
issued: 2023-05-30T11:16:43+00:00
language: en
modified: 2024-01-25T08:19:33+00:00
provenance: ProvenanceStatement
publisher: Erik Stam
temporal: PeriodOfTime
  end date: 2023-01-15T00:00:00+00:00
  start date: 2020-10-15T00:00:00+00:00
contact point: Kind
  fn: Erik Stam
  has UID: https://orcid.org/0000-0001-9827-0516
keyword: regional
keyword: human disease
keyword: COVID-19 phase
keyword: other
landing page: https://covid19initiatives.health-ri.nl/p/Project/27866022694516799
theme: http://purl.org/zonmw/covid19/10033
theme: http://purl.org/zonmw/covid19/10006
theme: http://purl.org/zonmw/generic/10006
theme: http://purl.org/zonmw/generic/10095

FU Castor Metingen BIA meting
type: Dataset
creator: Diana van Heemst
creator: Joris Deelen
creator: Marian Beekman
creator: Eline Slagboom
creator: Simon Mooijaart
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:47:47+00:00
language: en
modified: 2024-11-12T14:48:36+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

SignalingLipids Metabolomics
type: Dataset
creator: Marian Beekman
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Joris Deelen
creator: Eline Slagboom
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:14:20+00:00
language: en
modified: 2024-11-07T14:15:35+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

FU Castor Scores questionair toeval
type: Dataset
creator: Marian Beekman
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Eline Slagboom
creator: Joris Deelen
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:26:19+00:00
language: en
modified: 2024-11-12T14:27:00+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

LLS_IOP3_OLINKcardiomatebolic_metadata
type: Dataset
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Joris Deelen
creator: Marian Beekman
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-02-09T08:28:35+00:00
language: en
modified: 2024-02-09T08:29:02+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

IGF axis
type: Dataset
creator: Simon Mooijaart
creator: Marian Beekman
creator: Eline Slagboom
creator: Diana van Heemst
creator: Joris Deelen
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:21:23+00:00
language: en
modified: 2024-11-07T14:21:49+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Castor Metingen ECG
type: Dataset
creator: Diana van Heemst
creator: Marian Beekman
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Joris Deelen
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-07T15:23:41+00:00
language: en
modified: 2024-11-07T15:24:13+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Thyroid measures
type: Dataset
creator: Marian Beekman
creator: Joris Deelen
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Diana van Heemst
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:49:46+00:00
language: en
modified: 2024-11-07T14:50:15+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

FU_Castor_Thuis_vragenlijsten
type: Dataset
creator: Diana van Heemst
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Marian Beekman
creator: Joris Deelen
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T13:24:18+00:00
language: en
modified: 2024-11-12T13:26:07+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

LLS IOP2 Nightingale QL16-20
type: Dataset
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Diana van Heemst
creator: Marian Beekman
creator: Joris Deelen
description: From the group of 2,415 LLS PartnerOffspring that participated in the LLS between 2002 and 2006, 686 participants were examined for the second time between 2006 and 2008. In total 343 offspring and their partners (as couples living together) participated, with a mean age of 63 years. Of the 286 participants of the morning program, fasted blood was collected and serum/plasma was stored. Furthermore, skin replica’s and skin biopties were taken, from which viable fibroblasts were isolated and stored. The morning group was also subjected to an oral-glucose tolerance test. Of the 400 participants of the afternoon program, non-fasted blood was collected and serum/plasma and viable PBMCs were isolated and stored. The full blood was stimulated with LPS and cytokine levels were measured. From the majority of the total participants physical measures, DXA scan and standardized photographs of the face were taken, and all participants brought first morning void of urine which was stored.
issued: 2022-07-22T15:12:31+00:00
language: en
modified: 2022-08-09T15:05:46+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Q1_FFQ_Aminoacids
type: Dataset
creator: Marian Beekman
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Joris Deelen
creator: Diana van Heemst
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:59:52+00:00
language: en
modified: 2024-11-12T15:00:15+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

FU Castor Medicatiegebruik
type: Dataset
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Joris Deelen
creator: Eline Slagboom
creator: Marian Beekman
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:28:12+00:00
language: en
modified: 2024-11-12T14:28:31+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

IOP3_Partoffs
type: DatasetSeries
creator: Joris Deelen
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Marian Beekman
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2025-10-30T14:37:41.720505
modified: 2026-01-07T19:33:53.023818
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/

CIRGUIDANCERadiomics Zuyderland Ziekenhuis
type: Dataset
creator: Dr. Martijn Starmans
creator: Anouk de Jong
description: In this study, we aim to use a non-invasive radiomics alternative to predict the lymph node stage in patients with non-metastatic muscle-invasive bladder cancer. To this end, we will use the already gathered computed tomography (CT) data from the previously performed multicenter CIRGUIDANCE study. We would like to use the Trait XNAT to share the data among the hospitals.
issued: 2024-12-05T20:15:03+00:00
language: en
modified: 2024-12-05T20:15:03+00:00
provenance: ProvenanceStatement
publisher: Health-RI
contact point: Kind
  fn: Health-RI servicedesk
  has UID: example.com
theme: HEAL

Castor Medische voorgeschiedenis CCI
type: Dataset
creator: Marian Beekman
creator: Joris Deelen
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Diana van Heemst
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-07T15:24:48+00:00
language: en
modified: 2024-11-07T15:25:18+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

EuCanImage_GUMED_UC8
type: Dataset
creator: Ivan Bocharov
creator: Dr. Martijn Starmans
description: Within the EuCanImage project (https://eucanimage.eu/), imaging datasets are collected from multiple sites to facilitate the use of AI for cancer research. The BMIA XNAT will be used as main image data storage platform for centralized storage. As first usecase, breast cancer was identified, for which the first datasets will be collected from the University of Barcelona. The data will first be available to partners within the consortium, but will potentially be publicly released
issued: 2024-12-05T17:21:09+00:00
language: en
modified: 2024-12-05T17:21:09+00:00
provenance: ProvenanceStatement
publisher: Example publisher list
contact point: Kind
  fn: Example Data Management office
  has UID: example.com
theme: HEAL

FU survey Gevoel en gedrag (CES-D)
type: Dataset
creator: Marian Beekman
creator: Joris Deelen
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Diana van Heemst
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:19:43+00:00
language: en
modified: 2024-11-12T14:20:15+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

LLS IOP2 Gripstrength
type: Dataset
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Diana van Heemst
creator: Marian Beekman
creator: Joris Deelen
description: From the group of 2,415 LLS PartnerOffspring that participated in the LLS between 2002 and 2006, 686 participants were examined for the second time between 2006 and 2008. In total 343 offspring and their partners (as couples living together) participated, with a mean age of 63 years. Of the 286 participants of the morning program, fasted blood was collected and serum/plasma was stored. Furthermore, skin replica’s and skin biopties were taken, from which viable fibroblasts were isolated and stored. The morning group was also subjected to an oral-glucose tolerance test. Of the 400 participants of the afternoon program, non-fasted blood was collected and serum/plasma and viable PBMCs were isolated and stored. The full blood was stimulated with LPS and cytokine levels were measured. From the majority of the total participants physical measures, DXA scan and standardized photographs of the face were taken, and all participants brought first morning void of urine which was stored.
issued: 2022-07-22T15:16:01+00:00
language: en
modified: 2022-07-22T15:16:25+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

https://fdp-acc.healthdata.nl/dataset/8561b0d4-10b8-43ac-8d60-1fdb522adb40
type: Dataset
creator: Martijn Hendriks
description: Waarderend onderzoeken en ontwikkelen: leidt de toepassing van deze interventie in de teams van de Stichting Jeugdgezondheidszorg Zuid-Holland West tot het versterken en waarborgen van de mentale vitaliteit van medewerkers?
issued: 2023-12-18T14:39:08+00:00
language: en
modified: 2023-12-18T14:45:36+00:00
provenance: ProvenanceStatement
publisher: Martijn Hendriks
temporal: PeriodOfTime
  end date: 2023-12-15T00:00:00+00:00
  start date: 2022-12-15T00:00:00+00:00
title: Waarderend onderzoeken en ontwikkelen: leidt de toepassing van deze interventie in de teams van de Stichting Jeugdgezondheidszorg Zuid-Holland West tot het versterken en waarborgen van de mentale vitaliteit van medewerkers?
contact point: Kind
  fn: Martijn Hendriks
  has UID: https://orcid.org/0000-0002-9528-0871
landing page: https://covid19initiatives.health-ri.nl/p/Project/27866022694561626
theme: U07.1

EXCEPTIUS : Exceptional powers in time of Sars -CoV-2
type: Dataset
creator: Clara Egger
description: EXCEPTIUS : Exceptional powers in time of Sars -CoV-2
issued: 2023-03-15T08:54:12+00:00
language: en
modified: 2023-03-15T08:54:21+00:00
provenance: ProvenanceStatement
publisher: Clara Egger
temporal: PeriodOfTime
  end date: 2022-09-07T00:00:00+00:00
  start date: 2020-09-07T00:00:00+00:00
contact point: Kind
  fn: Clara Egger
  has UID: 0000-0001-7293-111X
keyword: target group of policy interventions
keyword: regional
keyword: international
keyword: national care public health measures
keyword: COVID-19 phase
keyword: other
keyword: national
landing page: https://covid19initiatives.health-ri.nl/p/Project/27866022694506515
theme: http://purl.org/zonmw/covid19/10007
theme: http://purl.org/zonmw/covid19/10033
theme: http://purl.org/zonmw/covid19/10098
theme: http://purl.org/zonmw/generic/10006
theme: http://purl.org/zonmw/covid19/10006
theme: http://purl.org/zonmw/covid19/10008

LLS IOP2 Clinical chemistry
type: Dataset
creator: Joris Deelen
creator: Marian Beekman
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Diana van Heemst
description: From the group of 2,415 LLS PartnerOffspring that participated in the LLS between 2002 and 2006, 686 participants were examined for the second time between 2006 and 2008. In total 343 offspring and their partners (as couples living together) participated, with a mean age of 63 years. Of the 286 participants of the morning program, fasted blood was collected and serum/plasma was stored. Furthermore, skin replica’s and skin biopties were taken, from which viable fibroblasts were isolated and stored. The morning group was also subjected to an oral-glucose tolerance test. Of the 400 participants of the afternoon program, non-fasted blood was collected and serum/plasma and viable PBMCs were isolated and stored. The full blood was stimulated with LPS and cytokine levels were measured. From the majority of the total participants physical measures, DXA scan and standardized photographs of the face were taken, and all participants brought first morning void of urine which was stored.
issued: 2022-07-22T15:14:19+00:00
language: en
modified: 2022-07-22T15:15:05+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

EGD
type: Dataset
creator: Marion Smits
creator: Sebastian van der Voort
creator: Dr. ir. Stefan Klein
description: FOR ACCESS TO THE DATASET: Do not request an account directly through the XNAT portal. If you would like to access the dataset please send an email to: servicedesk@health-ri.nl You will then be asked to sign the data usage agreement, and an account will be created for you. ACCESS REQUESTS DIRECTLY THROUGH THE XNAT PORTAL WILL NOT BE CONSIDERED. The Erasmus Glioma Database (EGD) is a collection of 774 patients with glioma. For this patients pre-operative imaging, genetic and histological data, and tumor segmentations are available. See the license for all conditions: check the file 'data_license.pdf' at Resources > PROJECT_DATA Some scans might have a poor image quality or errors due to registration issues. We have marked this scans as 'unacceptable' scan quality. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 952103
issued: 2024-12-05T17:21:07+00:00
language: en
modified: 2024-12-05T17:21:07+00:00
provenance: ProvenanceStatement
publisher: Example publisher list
contact point: Kind
  fn: Example Data Management office
  has UID: example.com
theme: HEAL

DEFENCE: Determination and Evaluation of the Frequency and Effects of myocardial damage iN patients with a SARS-CoV-2 infEction
type: Dataset
creator: Erik van Iperen
description: DEFENCE: Determination and Evaluation of the Frequency and Effects of myocardial damage iN patients with a SARS-CoV-2 infEction
issued: 2021-09-13T07:15:23+00:00
language: en
modified: 2021-09-20T11:43:48+00:00
provenance: ProvenanceStatement
publisher: Erik van Iperen
temporal: PeriodOfTime
  end date: 2023-10-01T00:00:00+00:00
  start date: 2021-10-01T00:00:00+00:00
contact point: Kind
  fn: Folkert W. Asselbergs
  has UID: https://orcid.org/0000-0002-1692-8669
keyword: home care
keyword: COVID-19
keyword: Acute myocardial infarction
keyword: human disease
keyword: Cardiac arrhythmia unspecified
keyword: COVID-19 phase
keyword: Heart failure
keyword: hospital care
keyword: GP care
keyword: national
keyword: Cerebrovascular diseases I60-I69
keyword: Myocarditis unspecified
keyword: COVID-19 patient grouping
landing page: https://covid19initiatives.health-ri.nl/p/Project/27866022694497953
theme: http://purl.org/zonmw/covid19/10033
theme: U07.1
theme: I51.4
theme: http://purl.org/zonmw/covid19/10091
theme: I60-I69
theme: I49.9
theme: http://purl.org/zonmw/covid19/10014
theme: http://purl.org/zonmw/covid19/10010
theme: I50
theme: http://purl.org/zonmw/generic/10095
theme: http://purl.org/zonmw/covid19/10012
theme: I21
theme: http://purl.org/zonmw/covid19/10007

Brain_MRI_WML_ERASMUS
type: Dataset
creator: prof.dr. Aad van der Lugt
description: This collection will include brain MRI scans on which the amount of white matter lesions (WML) will be quantified.
issued: 2024-12-05T20:15:02+00:00
language: en
modified: 2024-12-05T20:15:02+00:00
provenance: ProvenanceStatement
publisher: Health-RI
contact point: Kind
  fn: Health-RI servicedesk
  has UID: example.com
theme: HEAL

Timing and sequence of vaccination against COVID-19 and Influenza
type: Dataset
creator: Elisabeth Dulfer
description: Timing and sequence of vaccination against COVID-19 and Influenza
issued: 2021-09-09T08:32:43+00:00
language: en
modified: 2021-09-09T12:17:19+00:00
provenance: ProvenanceStatement
publisher: Elisabeth Dulfer
temporal: PeriodOfTime
  end date: 2022-09-01T00:00:00+00:00
  start date: 2021-10-01T00:00:00+00:00
contact point: Kind
  fn: Josephine van de Maat
  has UID: https://orcid.org/0000-0001-7351-4596
keyword: GP care
keyword: national
keyword: people by age
keyword: human disease
keyword: Codes for special purposes U00-U85
keyword: COVID-19 phase
landing page: https://covid19initiatives.health-ri.nl/p/Project/27866022694497950
theme: http://purl.org/zonmw/covid19/10038
theme: http://purl.org/zonmw/generic/10095
theme: http://purl.org/zonmw/covid19/10012
theme: U00-U85
theme: http://purl.org/zonmw/covid19/10007
theme: http://purl.org/zonmw/covid19/10033

LLS IOP2 Participant info
type: Dataset
creator: Joris Deelen
creator: Eline Slagboom
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Marian Beekman
description: From the group of 2,415 LLS PartnerOffspring that participated in the LLS between 2002 and 2006, 686 participants were examined for the second time between 2006 and 2008. In total 343 offspring and their partners (as couples living together) participated, with a mean age of 63 years. Of the 286 participants of the morning program, fasted blood was collected and serum/plasma was stored. Furthermore, skin replica’s and skin biopties were taken, from which viable fibroblasts were isolated and stored. The morning group was also subjected to an oral-glucose tolerance test. Of the 400 participants of the afternoon program, non-fasted blood was collected and serum/plasma and viable PBMCs were isolated and stored. The full blood was stimulated with LPS and cytokine levels were measured. From the majority of the total participants physical measures, DXA scan and standardized photographs of the face were taken, and all participants brought first morning void of urine which was stored.
issued: 2022-07-22T15:18:08+00:00
language: en
modified: 2022-07-22T15:18:37+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

FU Castor Thuis biomateriaal
type: Dataset
creator: Marian Beekman
creator: Eline Slagboom
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Joris Deelen
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:45:40+00:00
language: en
modified: 2024-11-12T14:46:05+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Q1 FFQ Fooditems
type: Dataset
creator: Marian Beekman
creator: Joris Deelen
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Eline Slagboom
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:51:09+00:00
language: en
modified: 2024-11-12T14:52:12+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

LLS_IOP1_partoffs_Demography
type: Dataset
creator: Simon Mooijaart
creator: Joris Deelen
creator: Marian Beekman
creator: Diana van Heemst
creator: Eline Slagboom
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79) as population based controls. It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Partner Offspring consists of the 1671 offspring of nonagenarian siblings and their 744 partners from 421 families of whom we have physical measurements, biosamples, biomarkers, and questionnaire data. We followed this group of 2,415 middle-aged participants for their vital status till 2020, for their morbidity status till 2017.
issued: 2024-11-07T13:31:37+00:00
language: en
modified: 2024-11-07T13:32:54+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

LLS IOP2 BIA Body Composition
type: Dataset
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Marian Beekman
creator: Joris Deelen
creator: Diana van Heemst
description: From the group of 2,415 LLS PartnerOffspring that participated in the LLS between 2002 and 2006, 686 participants were examined for the second time between 2006 and 2008. In total 343 offspring and their partners (as couples living together) participated, with a mean age of 63 years. Of the 286 participants of the morning program, fasted blood was collected and serum/plasma was stored. Furthermore, skin replica’s and skin biopties were taken, from which viable fibroblasts were isolated and stored. The morning group was also subjected to an oral-glucose tolerance test. Of the 400 participants of the afternoon program, non-fasted blood was collected and serum/plasma and viable PBMCs were isolated and stored. The full blood was stimulated with LPS and cytokine levels were measured. From the majority of the total participants physical measures, DXA scan and standardized photographs of the face were taken, and all participants brought first morning void of urine which was stored.
issued: 2022-07-22T15:19:08+00:00
language: en
modified: 2022-07-22T15:19:38+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Q1 FFQ key food groups 20200911
type: Dataset
creator: Eline Slagboom
creator: Marian Beekman
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Joris Deelen
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T15:00:58+00:00
language: en
modified: 2024-11-12T15:01:33+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Demography
type: Dataset
creator: Eline Slagboom
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Joris Deelen
creator: Marian Beekman
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2022-04-29T08:16:26+00:00
language: en
modified: 2022-06-13T12:01:05+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Gut Microbiome related data
type: Dataset
creator: Simon Mooijaart
creator: Marian Beekman
creator: Joris Deelen
creator: Eline Slagboom
creator: Diana van Heemst
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2022-04-29T08:09:36+00:00
language: en
modified: 2022-06-13T12:01:18+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

BEAT COVID Info LUMC
type: Dataset
access rights: RESTRICTED
creator: Mariet C.W. Feltkamp
creator: Frank J.T. Staal
creator: Maria Yazdanbakhsh
creator: Simon P. Jochems
creator: Roula Tsonaka
creator: Jutte J.C. de Vries
creator: Anne M. van der Does
creator: Simone A. Joosten
creator: Eric J. Snijder
creator: Bernard M. van den Berg
creator: Cornelis H. Hokke
creator: Jelle J. Goeman
creator: Suzanne Cannegieter
creator: Jacqueline J. Janse
creator: Meta Roestenberg
creator: Hermelijn H. Smits
creator: Michael R. del Prado
creator: Lieke Lamont
creator: Jeroen Eikenboom
creator: Jeanette Wigbers
creator: Annemieke Geluk
creator: Anna Roukens, , Principal Investigator of the LUMC BEAT COVID group
creator: Leendert A. Trouw
creator: Martin Giera
creator: Aswin Verhoeven
creator: Thomas Hankemeier
creator: Henk J. van der Wijk
creator: Pieter S. Hiemstra
creator: Manfred Wuhrer
creator: M. Sesmu Arbous
creator: Tom H.M. Ottenhoff
creator: Mirjam H.M. Heemskerk
creator: T. Pongracz
creator: David J. van Westerloo
creator: Christa M. Cobbaert
creator: Leo G. Visser
creator: Robin C. van Wissen
creator: Marjolein Kikkert
creator: Jacques J.M. van Dongen
creator: Judith Manniën
description: BEAT COVID Info LUMC: Research laboratory data of LUMC BEAT COVID cohort. Prospective observational WMO study including 191 COVID-19 patients from April 2020 to March 2021. Over 400 different laboratory variables were measured, listed in the attached tables. Principle Investigator, Anna Roukens, LUCID. Website: https://w3id.org/lumc/lucid/beatcovid_info
is referenced by: j.isci.2024.110374
is referenced by: s41590-021-01095-w
is referenced by: s41598-024-63586-8
is referenced by: j.isci.2022.105873
is referenced by: j.ebiom.2022.103957
is referenced by: j.lanmic.2024.07.005
is referenced by: cells11172743
is referenced by: journal.pone.0291212
issued: 2024-02-04T00:00:00+00:00
language: en
modified: 2024-02-04T00:00:00+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center, the Netherlands
contact point: Kind
  fn: Anna Roukens, Principle Investigator, Dept. LUCID, https://orcid.org/0000-0002-1397-0992
keyword: COVID-19
theme: HEAL

Survey Levensorientatie vragenlijst
type: Dataset
creator: Eline Slagboom
creator: Diana van Heemst
creator: Marian Beekman
creator: Simon Mooijaart
creator: Joris Deelen
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-07T15:26:03+00:00
language: en
modified: 2024-11-07T15:26:49+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Plasma endothelial markers
type: Dataset
creator: Eline Slagboom
creator: Joris Deelen
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Marian Beekman
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:46:33+00:00
language: en
modified: 2024-11-07T14:47:12+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

CVON MIND AF
type: Dataset
creator: Eelco Soeteman
creator: Annemarie Scholman
creator: Cornelis Allaart
creator: Don van Velzen
description: Brein MRIs van patiënten met permanent AF
issued: 2024-12-05T20:15:03+00:00
language: en
modified: 2024-12-05T20:15:03+00:00
provenance: ProvenanceStatement
publisher: Health-RI
contact point: Kind
  fn: Health-RI servicedesk
  has UID: example.com
theme: HEAL

IOP1_Partoffs
type: DatasetSeries
creator: Joris Deelen
creator: Eline Slagboom
creator: Marian Beekman
creator: Simon Mooijaart
creator: Diana van Heemst
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79) as population based controls. It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Partner Offspring consists of the 1671 offspring of nonagenarian siblings and their 744 partners from 421 families of whom we have physical measurements, biosamples, biomarkers, and questionnaire data. We followed this group of 2,415 middle-aged participants for their vital status till 2020, for their morbidity status till 2017.
issued: 2025-10-30T14:39:05.634673
modified: 2026-01-07T19:33:41.058351
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/

LLS_IOP3_OLINKcardiomatebolic_measures
type: Dataset
creator: Marian Beekman
creator: Joris Deelen
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Diana van Heemst
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-02-09T08:26:50+00:00
language: en
modified: 2024-02-09T08:27:25+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Leiden NMR
type: Dataset
creator: Diana van Heemst
creator: Eline Slagboom
creator: Marian Beekman
creator: Joris Deelen
creator: Simon Mooijaart
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2022-04-29T08:13:18+00:00
language: en
modified: 2022-06-13T12:03:33+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

BEAT COVID Lab results LUMC
type: Dataset
access rights: RESTRICTED
creator: Simone A. Joosten
creator: Aswin Verhoeven
creator: Martin Giera
creator: Jeroen Eikenboom
creator: Jelle J. Goeman
creator: Eric J. Snijder
creator: Michael R. del Prado
creator: Mariet C.W. Feltkamp
creator: Roula Tsonaka
creator: Jeanette Wigbers
creator: Bernard M. van den Berg
creator: Judith Manniën
creator: Marjolein Kikkert
creator: Maria Yazdanbakhsh
creator: Anna Roukens, , Principal Investigator of the LUMC BEAT COVID group
creator: Cornelis H. Hokke
creator: Robin C. van Wissen
creator: Thomas Hankemeier
creator: T. Pongracz
creator: Pieter S. Hiemstra
creator: Suzanne Cannegieter
creator: Anne M. van der Does
creator: Lieke Lamont
creator: Frank J.T. Staal
creator: Mirjam H.M. Heemskerk
creator: Simon P. Jochems
creator: Annemieke Geluk
creator: Jutte J.C. de Vries
creator: Jacqueline J. Janse
creator: Leendert A. Trouw
creator: Leo G. Visser
creator: David J. van Westerloo
creator: Henk J. van der Wijk
creator: Tom H.M. Ottenhoff
creator: Jacques J.M. van Dongen
creator: M. Sesmu Arbous
creator: Manfred Wuhrer
creator: Meta Roestenberg
creator: Christa M. Cobbaert
creator: Hermelijn H. Smits
description: BEAT COVID Lab results LUMC: Research laboratory data of LUMC BEAT COVID cohort. Prospective observational WMO study including 191 COVID-19 patients from April 2020 to March 2021. Over 400 different laboratory variables were measured, listed in the attached tables. Principle Investigator, Anna Roukens, LUCID. Website: https://w3id.org/lumc/lucid/beatcovid_labmeasurements
is referenced by: j.lanmic.2024.07.005
is referenced by: cells11172743
is referenced by: journal.pone.0291212
is referenced by: j.isci.2024.110374
is referenced by: s41590-021-01095-w
is referenced by: s41598-024-63586-8
is referenced by: j.isci.2022.105873
is referenced by: j.ebiom.2022.103957
issued: 2024-02-04T00:00:00+00:00
language: en
modified: 2024-02-04T00:00:00+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center, the Netherlands
contact point: Kind
  fn: Anna Roukens, Principle Investigator, Dept. LUCID, https://orcid.org/0000-0002-1397-0992
keyword: COVID-19
theme: HEAL

FU_Nightingale_2024
type: Dataset
creator: Eline Slagboom
creator: Marian Beekman
creator: Simon Mooijaart
creator: Joris Deelen
creator: Diana van Heemst
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:32:45+00:00
language: en
modified: 2024-11-12T14:43:50+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

FU Castor Bloedafname
type: Dataset
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Marian Beekman
creator: Joris Deelen
creator: Diana van Heemst
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:27:23+00:00
language: en
modified: 2024-11-12T14:27:46+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

AFRICAI_MICCAI2024_CTSpine1K
type: Dataset
creator: Yang Deng
description: Collection of data from the MICCAI 2024 CTSpine1K Dataset as part of the EuCanImage sponsored AFRICAI repository. In this repository, we introduce a large-scale spine CT dataset called CTSpine1K, curated from multiple sources for vertebra segmentation, which contains 1,005 CT volumes with over 500,000 labeled vertebrae slices and 11,172 vertebrae belonging to different spinal conditions. The data within this work is licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (CC BY-NC-SA 4.0) If you use our dataset, please cite our paper: Yang Deng, Ce Wang, Yuan Hui, et al. CtSpine1k: A large-scale dataset for spinal vertebrae segmentation in computed tomography. arXiv preprint arXiv:2105.14711 (2021).
issued: 2024-12-09T10:47:27+00:00
language: en
modified: 2024-12-09T10:47:27+00:00
provenance: ProvenanceStatement
publisher: Health-RI
contact point: Kind
  fn: Health-RI servicedesk
  has UID: example.com
keyword: Image
keyword: Medical
keyword: Dataset
keyword: Segmentation
keyword: Spine
theme: HEAL

MRI Data
type: Dataset
creator: Eline Slagboom
creator: Joris Deelen
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Marian Beekman
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:48:28+00:00
language: en
modified: 2024-11-07T14:48:59+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

COMODULATE Lab results LUMC
type: Dataset
access rights: RESTRICTED
creator: Simon P. Jochems
creator: Jutte J.C. de Vries, Principal Investigator
description: COMODULATE Lab results LUMC: Research laboratory data of the LUMC COMODULATE cohort. Retrospective observational non-WMO study including COVID-19 and Influenza patients with and without ARDS from 2019 to 2024. Host transcriptomics and inflammatory proteomics variables were measured in respiratory samples. Principle Investigator, Jutte JC de Vries, LUCID. Website: https://w3id.org/lumc/lucid/comodulate_labmeasurements
is referenced by: personalised-targeted-immunomodulation-patients-ards-related-covid19-and-future-pandemic
issued: 2025-04-04T00:00:00+00:00
language: en
modified: 2025-04-04T00:00:00+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center, the Netherlands
contact point: Kind
  fn: Jutte J.C. de Vries, Principle Investigator, Dept. LUCID, https://orcid.org/0000-0003-2530-6260
keyword: Influenza
keyword: COVID-19
keyword: transcriptomics
theme: HEAL

LLS Questionnaire 1
type: DatasetSeries
creator: Simon Mooijaart
creator: Marian Beekman
creator: Diana van Heemst
creator: Joris Deelen
creator: Eline Slagboom
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2025-10-30T14:39:40.535847
modified: 2026-01-07T19:33:49.573403
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/

Een onverwachte valse start op de arbeidsmarkt
type: Dataset
creator: Bas ter Weel
description: Een onverwachte valse start op de arbeidsmarkt
issued: 2023-03-10T12:53:20+00:00
language: en
modified: 2023-03-10T14:29:18+00:00
provenance: ProvenanceStatement
publisher: Bas ter Weel
temporal: PeriodOfTime
  end date: 2022-12-31T00:00:00+00:00
  start date: 2020-09-01T00:00:00+00:00
contact point: Kind
  fn: Bas ter Weel
  has UID: https://orcid.org/0000-0001-8446-7457
keyword: Effects COVID on participation
keyword: other
keyword: national
keyword: COVID-19
keyword: people by education
keyword: human disease
keyword: COVID-19 phase
landing page: https://covid19initiatives.health-ri.nl/p/Project/27866022694506050
theme: http://purl.org/zonmw/covid19/10060
theme: http://purl.org/zonmw/generic/10095
theme: http://purl.org/zonmw/covid19/10007
theme: http://purl.org/zonmw/covid19/10033
theme: http://purl.org/zonmw/generic/10006

Q1 FFQ Food group key
type: Dataset
creator: Joris Deelen
creator: Marian Beekman
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Eline Slagboom
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:53:44+00:00
language: en
modified: 2024-11-12T14:54:30+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

FU survey Kwaliteit van leven (EQ-5D)
type: Dataset
creator: Joris Deelen
creator: Diana van Heemst
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Marian Beekman
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T10:45:40+00:00
language: en
modified: 2024-11-12T10:49:39+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

FU survey Alg vragenlijst LLS
type: Dataset
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Marian Beekman
creator: Diana van Heemst
creator: Joris Deelen
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T10:51:13+00:00
language: en
modified: 2024-11-12T10:52:52+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

BEAT COVID Severity Score LUMC
type: Dataset
access rights: RESTRICTED
creator: Frank J.T. Staal
creator: Jacqueline J. Janse
creator: Maria Yazdanbakhsh
creator: Bernard M. van den Berg
creator: Henk J. van der Wijk
creator: Annemieke Geluk
creator: Aswin Verhoeven
creator: M. Sesmu Arbous
creator: Cornelis H. Hokke
creator: Lieke Lamont
creator: Jacques J.M. van Dongen
creator: Jeroen Eikenboom
creator: Eric J. Snijder
creator: Robin C. van Wissen
creator: Jutte J.C. de Vries
creator: Anne M. van der Does
creator: Jelle J. Goeman
creator: Leendert A. Trouw
creator: Suzanne Cannegieter
creator: Leo G. Visser
creator: Meta Roestenberg
creator: Anna Roukens, , Principal Investigator of the LUMC BEAT COVID group
creator: T. Pongracz
creator: Mirjam H.M. Heemskerk
creator: Marjolein Kikkert
creator: Michael R. del Prado
creator: Simon P. Jochems
creator: Tom H.M. Ottenhoff
creator: Thomas Hankemeier
creator: Pieter S. Hiemstra
creator: Manfred Wuhrer
creator: Mariet C.W. Feltkamp
creator: Roula Tsonaka
creator: Hermelijn H. Smits
creator: Jeanette Wigbers
creator: Christa M. Cobbaert
creator: Simone A. Joosten
creator: Martin Giera
creator: Judith Manniën
creator: David J. van Westerloo
description: BEAT COVID Severity Score LUMC: Research laboratory data of LUMC BEAT COVID cohort. Prospective observational WMO study including 191 COVID-19 patients from April 2020 to March 2021. Over 400 different laboratory variables were measured, listed in the attached tables. Principle Investigator, Anna Roukens, LUCID. Website: https://w3id.org/lumc/lucid/beatcovid_severityscores
is referenced by: j.isci.2024.110374
is referenced by: s41590-021-01095-w
is referenced by: s41598-024-63586-8
is referenced by: j.isci.2022.105873
is referenced by: j.ebiom.2022.103957
is referenced by: j.lanmic.2024.07.005
is referenced by: cells11172743
is referenced by: journal.pone.0291212
issued: 2024-02-04T00:00:00+00:00
language: en
modified: 2024-02-04T00:00:00+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center, the Netherlands
contact point: Kind
  fn: Anna Roukens, Principle Investigator, Dept. LUCID, https://orcid.org/0000-0002-1397-0992
keyword: COVID-19
theme: HEAL

Cellcounts
type: Dataset
creator: Joris Deelen
creator: Simon Mooijaart
creator: Marian Beekman
creator: Eline Slagboom
creator: Diana van Heemst
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79) as population based controls. It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Partner Offspring consists of the 1671 offspring of nonagenarian siblings and their 744 partners from 421 families of whom we have physical measurements, biosamples, biomarkers, and questionnaire data. We followed this group of 2,415 middle-aged participants for their vital status till 2020, for their morbidity status till 2017.
issued: 2022-05-10T12:29:13+00:00
language: en
modified: 2022-06-13T12:02:08+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

FU Castor Metingen algemeen
type: Dataset
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Marian Beekman
creator: Joris Deelen
creator: Eline Slagboom
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:49:57+00:00
language: en
modified: 2024-11-12T14:50:24+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Global Metabolomics Overview
type: Dataset
creator: Joris Deelen
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Diana van Heemst
creator: Marian Beekman
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T13:59:53+00:00
language: en
modified: 2024-11-07T14:00:36+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

FU survey Fysieke functie ADL IADL
type: Dataset
creator: Simon Mooijaart
creator: Joris Deelen
creator: Diana van Heemst
creator: Marian Beekman
creator: Eline Slagboom
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:44:26+00:00
language: en
modified: 2024-11-12T14:45:08+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Plasma Amyloid markers
type: Dataset
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Marian Beekman
creator: Eline Slagboom
creator: Joris Deelen
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:19:37+00:00
language: en
modified: 2024-11-07T14:20:21+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

IOP2_Partoffs
type: DatasetSeries
creator: Joris Deelen
creator: Marian Beekman
creator: Eline Slagboom
creator: Diana van Heemst
creator: Simon Mooijaart
description: From the group of 2,415 LLS PartnerOffspring that participated in the LLS between 2002 and 2006, 686 participants were examined for the second time between 2006 and 2008. In total 343 offspring and their partners (as couples living together) participated, with a mean age of 63 years. Of the 286 participants of the morning program, fasted blood was collected and serum/plasma was stored. Furthermore, skin replica’s and skin biopties were taken, from which viable fibroblasts were isolated and stored. The morning group was also subjected to an oral-glucose tolerance test. Of the 400 participants of the afternoon program, non-fasted blood was collected and serum/plasma and viable PBMCs were isolated and stored. The full blood was stimulated with LPS and cytokine levels were measured. From the majority of the total participants physical measures, DXA scan and standardized photographs of the face were taken, and all participants brought first morning void of urine which was stored.
issued: 2025-10-30T14:39:27.114788
modified: 2026-01-07T19:34:34.357576
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/

Cell counts
type: Dataset
creator: Eline Slagboom
creator: Diana van Heemst
creator: Joris Deelen
creator: Marian Beekman
creator: Simon Mooijaart
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2022-04-29T08:14:14+00:00
language: en
modified: 2022-09-09T16:24:35+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Healthcare utilization in primary care during the corona pandemic: a nation-wide population-based study from a patient and healthcare provider perspective
type: Dataset
creator: Evelien de Schepper
description: Healthcare utilization in primary care during the corona pandemic: a nation-wide population-based study from a patient and healthcare provider perspective
issued: 2021-09-29T14:15:22+00:00
language: en
modified: 2021-09-29T14:28:20+00:00
provenance: ProvenanceStatement
publisher: Evelien de Schepper
temporal: PeriodOfTime
  end date: 2022-03-01T00:00:00+00:00
  start date: 2020-09-01T00:00:00+00:00
contact point: Kind
  fn: Evelien de Schepper
  has UID: https://orcid.org/0000-0002-1896-6343
keyword: human disease
keyword: COVID-19 phase
keyword: GP care
keyword: Cerebral infarction
keyword: national
keyword: people by age
landing page: https://covid19initiatives.health-ri.nl/p/Project/27866022694498246
theme: I63
theme: http://purl.org/zonmw/covid19/10038
theme: http://purl.org/zonmw/generic/10095
theme: http://purl.org/zonmw/covid19/10012
theme: http://purl.org/zonmw/covid19/10007
theme: http://purl.org/zonmw/covid19/10033

Lanadelumab for Treatment of COVID-19 Disease
type: Dataset
creator: Job Engel
description: Lanadelumab for Treatment of COVID-19 Disease
issued: 2023-09-10T20:18:50+00:00
language: en
modified: 2023-09-11T08:21:06+00:00
provenance: ProvenanceStatement
publisher: Job Engel
temporal: PeriodOfTime
  end date: 2021-09-05T00:00:00+00:00
  start date: 2020-09-05T00:00:00+00:00
contact point: Kind
  fn: Frank van de Veerdonk
  has UID: https://orcid.org/0000-0002-1121-4894
keyword: national
keyword: COVID-19 patient grouping
keyword: COVID-19 U07.1
keyword: human disease
keyword: COVID-19 phase
keyword: hospital care
keyword: health care phase
keyword: other
landing page: https://covid19initiatives.health-ri.nl/p/Project/27866022694542657
theme: http://purl.org/zonmw/covid19/10007
theme: http://purl.org/zonmw/covid19/10033
theme: http://purl.org/zonmw/covid19/10018
theme: http://purl.org/zonmw/covid19/10091
theme: http://purl.org/zonmw/generic/10006
theme: http://purl.org/zonmw/covid19/10014
theme: http://purl.org/zonmw/generic/10095

Clinicalchemistry
type: Dataset
creator: Diana van Heemst
creator: Eline Slagboom
creator: Joris Deelen
creator: Marian Beekman
creator: Simon Mooijaart
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2024-11-07T13:37:47+00:00
language: en
modified: 2024-11-07T13:38:13+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

LLS IOP3 Partoffs Apolipoprotein platform
type: Dataset
creator: Diana van Heemst
creator: Joris Deelen
creator: Marian Beekman
creator: Eline Slagboom
creator: Simon Mooijaart
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2022-07-22T15:05:06+00:00
language: en
modified: 2022-07-22T15:05:56+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

FU survey Fysieke activiteit (SQUASH)
type: Dataset
creator: Diana van Heemst
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Joris Deelen
creator: Marian Beekman
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:46:49+00:00
language: en
modified: 2024-11-12T14:47:15+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Cognition_questions
type: Dataset
creator: Joris Deelen
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Marian Beekman
creator: Diana van Heemst
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:22:43+00:00
language: en
modified: 2024-11-07T14:45:07+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Caging the dragon: translational approach to unravel and prevent COVID-19 associated thrombosis (10430012010004)
type: Dataset
creator: Eva Kempers
creator: Chantal Visser
description: Caging the dragon: translational approach to unravel and prevent COVID-19 associated thrombosis (10430012010004)
issued: 2023-05-23T14:39:28+00:00
language: en
modified: 2023-05-23T14:41:08+00:00
provenance: ProvenanceStatement
publisher: Chantal Chantal
temporal: PeriodOfTime
  end date: 2024-01-01T00:00:00+00:00
  start date: 2020-05-01T00:00:00+00:00
contact point: Kind
  fn: Marieke Kruip
  has UID: https://orcid.org/0000-0002-0265-4871
keyword: regional
keyword: local
keyword: COVID-19 phase
keyword: human disease
keyword: hospital care
keyword: health care phase
keyword: Pulmonary heart disease and diseases of pulmonary circulation I26-I28
keyword: other
keyword: Diseases of veins lymphatic vessels and lymph nodes not elsewhere classified I80-I89
keyword: residential care
keyword: outpatient care
keyword: nursing home care
keyword: national
keyword: COVID-19 patient grouping
keyword: home care
keyword: people by age
keyword: COVID-19 vaccination grouping
landing page: https://covid19initiatives.health-ri.nl/p/Project/27866022694514811
theme: http://purl.org/zonmw/covid19/10013
theme: http://purl.org/zonmw/covid19/10091
theme: http://purl.org/zonmw/covid19/10006
theme: http://purl.org/zonmw/generic/10006
theme: http://purl.org/zonmw/covid19/10018
theme: I26-I28
theme: I80-I89
theme: http://purl.org/zonmw/covid19/10220
theme: http://purl.org/zonmw/covid19/10017
theme: http://purl.org/zonmw/covid19/10038
theme: http://purl.org/zonmw/covid19/10014
theme: http://purl.org/zonmw/covid19/10010
theme: http://purl.org/zonmw/generic/10095
theme: http://purl.org/zonmw/covid19/10016
theme: http://purl.org/zonmw/covid19/10005
theme: http://purl.org/zonmw/covid19/10007
theme: http://purl.org/zonmw/covid19/10033

FU Castor Metingen bloeddruk
type: Dataset
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Joris Deelen
creator: Diana van Heemst
creator: Marian Beekman
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T13:48:58+00:00
language: en
modified: 2024-11-12T14:17:04+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Q1 FFQ Macronutrients
type: Dataset
creator: Joris Deelen
creator: Marian Beekman
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Eline Slagboom
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:55:12+00:00
language: en
modified: 2024-11-12T14:55:53+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

FU survey Fysieke activeit (SQUASH) OUD
type: Dataset
creator: Marian Beekman
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Joris Deelen
creator: Eline Slagboom
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T10:43:54+00:00
language: en
modified: 2024-11-12T10:44:55+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

FU survey Darmgezondheid (GSRS)
type: Dataset
creator: Eline Slagboom
creator: Diana van Heemst
creator: Marian Beekman
creator: Joris Deelen
creator: Simon Mooijaart
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:28:57+00:00
language: en
modified: 2024-11-12T14:29:46+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Castor Cognitietesten
type: Dataset
creator: Marian Beekman
creator: Joris Deelen
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Diana van Heemst
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-07T14:51:25+00:00
language: en
modified: 2024-11-07T14:52:03+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

FU Castor Balanstesten
type: Dataset
creator: Joris Deelen
creator: Simon Mooijaart
creator: Marian Beekman
creator: Eline Slagboom
creator: Diana van Heemst
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:31:19+00:00
language: en
modified: 2024-11-12T14:31:43+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

BIGR[eye] EMC
type: Dataset
creator: Dr. Luisa Sanchez Brea
creator: Dr. Danilo Andrade De Jesus
description: Data collected within the eye research group of the Biomedical Imaging Group Rotterdam, Erasmus MC
issued: 2024-12-05T20:15:02+00:00
language: en
modified: 2024-12-05T20:15:02+00:00
provenance: ProvenanceStatement
publisher: Health-RI
contact point: Kind
  fn: Health-RI servicedesk
  has UID: example.com
theme: HEAL

https://ckan-acc.healthdata.nl/catalog.jsonld
type: PagedCollection
items per page: 100
last: https://ckan-acc.healthdata.nl/catalog.jsonld
last page: https://ckan-acc.healthdata.nl/catalog.jsonld
next: https://ckan-acc.healthdata.nl/catalog.jsonld
next page: https://ckan-acc.healthdata.nl/catalog.jsonld
total items: 772

FU Castor Metingen handknijpkrachttest
type: Dataset
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Eline Slagboom
creator: Marian Beekman
creator: Joris Deelen
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T13:27:39+00:00
language: en
modified: 2024-11-12T13:37:41+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

FU Castor Metingen Longfunctie
type: Dataset
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Diana van Heemst
creator: Joris Deelen
creator: Marian Beekman
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:18:42+00:00
language: en
modified: 2024-11-12T14:19:10+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

LLS Follow Up study
type: DatasetSeries
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Marian Beekman
creator: Eline Slagboom
creator: Joris Deelen
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2025-10-30T14:40:24.332549
modified: 2026-01-07T19:34:11.242716
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/

LLS IOP3 Nightingale QL16-20
type: Dataset
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Joris Deelen
creator: Eline Slagboom
creator: Marian Beekman
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2022-07-22T15:08:02+00:00
language: en
modified: 2022-07-22T15:08:40+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

AILS
type: Dataset
creator: Maarten Thomeer
description: Retrospective analysis of atypical iso intense lesions after Primovist injection
issued: 2024-12-09T10:47:27+00:00
language: en
modified: 2024-12-09T10:47:27+00:00
provenance: ProvenanceStatement
publisher: Health-RI
contact point: Kind
  fn: Health-RI servicedesk
  has UID: example.com
theme: HEAL

SignalingLipids Dictionary
type: Dataset
creator: Simon Mooijaart
creator: Joris Deelen
creator: Eline Slagboom
creator: Diana van Heemst
creator: Marian Beekman
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:11:04+00:00
language: en
modified: 2024-11-07T14:11:40+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Nivel Primary Care General Practices 2012
type: Dataset
applicable legislation: oj
access rights: NON PUBLIC
creator: Nivel
description: Electronic health record data from general practices spread throughout the Netherlands. General practice care comprises regular healthcare provision during normal practice hours, excluding out-of-hours primary care, emergency care and hospital admissions
issued: 2025-11-04T16:23:24.322884
language: en
modified: 2026-01-07T19:31:47.146175
provenance: ProvenanceStatement
publisher: Nivel
contact point: Kind
  fn: Leontien Korteweg
keyword: EHR
keyword: Electronic Health Records EHR
keyword: Primary Care
keyword: Routine Healthcare Data
theme: HEAL

Nightingale
type: Dataset
creator: Joris Deelen
creator: Marian Beekman
creator: Eline Slagboom
creator: Diana van Heemst
creator: Simon Mooijaart
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2022-04-29T08:17:24+00:00
language: en
modified: 2022-06-13T12:01:38+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

LLS IOP2 blood pressure
type: Dataset
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Joris Deelen
creator: Eline Slagboom
creator: Marian Beekman
description: From the group of 2,415 LLS PartnerOffspring that participated in the LLS between 2002 and 2006, 686 participants were examined for the second time between 2006 and 2008. In total 343 offspring and their partners (as couples living together) participated, with a mean age of 63 years. Of the 286 participants of the morning program, fasted blood was collected and serum/plasma was stored. Furthermore, skin replica’s and skin biopties were taken, from which viable fibroblasts were isolated and stored. The morning group was also subjected to an oral-glucose tolerance test. Of the 400 participants of the afternoon program, non-fasted blood was collected and serum/plasma and viable PBMCs were isolated and stored. The full blood was stimulated with LPS and cytokine levels were measured. From the majority of the total participants physical measures, DXA scan and standardized photographs of the face were taken, and all participants brought first morning void of urine which was stored.
issued: 2022-07-22T15:17:12+00:00
language: en
modified: 2022-07-22T15:17:37+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Visit measures
type: Dataset
creator: Joris Deelen
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Diana van Heemst
creator: Marian Beekman
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2022-04-29T08:15:08+00:00
language: en
modified: 2022-06-13T12:03:59+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

FU survey Voedingsvragenlijst (FFQ)
type: Dataset
creator: Joris Deelen
creator: Eline Slagboom
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Marian Beekman
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:30:27+00:00
language: en
modified: 2024-11-12T14:30:55+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

LLS_IOP1_partoffs_LeidenNMR_Kimble
type: Dataset
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Joris Deelen
creator: Eline Slagboom
creator: Marian Beekman
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79) as population based controls. It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Partner Offspring consists of the 1671 offspring of nonagenarian siblings and their 744 partners from 421 families of whom we have physical measurements, biosamples, biomarkers, and questionnaire data. We followed this group of 2,415 middle-aged participants for their vital status till 2020, for their morbidity status till 2017.
issued: 2022-05-10T13:13:42+00:00
language: en
modified: 2022-06-13T12:02:47+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Participant information
type: Dataset
creator: Joris Deelen
creator: Eline Slagboom
creator: Marian Beekman
creator: Diana van Heemst
creator: Simon Mooijaart
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2022-04-28T15:40:58+00:00
language: en
modified: 2022-06-13T12:03:46+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Clinical Chemistry
type: Dataset
creator: Diana van Heemst
creator: Eline Slagboom
creator: Joris Deelen
creator: Marian Beekman
creator: Simon Mooijaart
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79) as population based controls. It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Partner Offspring consists of the 1671 offspring of nonagenarian siblings and their 744 partners from 421 families of whom we have physical measurements, biosamples, biomarkers, and questionnaire data. We followed this group of 2,415 middle-aged participants for their vital status till 2020, for their morbidity status till 2017.
issued: 2024-11-07T13:35:33+00:00
language: en
modified: 2024-11-07T13:36:41+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

SignalingLipids Overview
type: Dataset
creator: Diana van Heemst
creator: Eline Slagboom
creator: Joris Deelen
creator: Simon Mooijaart
creator: Marian Beekman
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:12:43+00:00
language: en
modified: 2024-11-07T14:13:14+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

FU Castor Welkom
type: Dataset
creator: Joris Deelen
creator: Marian Beekman
creator: Diana van Heemst
creator: Eline Slagboom
creator: Simon Mooijaart
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:49:04+00:00
language: en
modified: 2024-11-12T14:49:29+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

IOP1_Sibs
type: DatasetSeries
creator: Marian Beekman
creator: Joris Deelen
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Diana van Heemst
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2025-10-30T14:39:11.882072
modified: 2026-01-07T19:33:28.046511
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/